000			03822nam a22004455i 4500
001			978-1-59259-905-9
003			DE-He213
005			20161121230555.0
007			cr nn 008mamaa
008			100301s2005 xxu| s |||| 0|eng d
020			_a9781592599059 _9978-1-59259-905-9
024	7		_a10.1385/1592599052 _2doi
050		4	_aRC346-429.2
072		7	_aMJN _2bicssc
072		7	_aMED056000 _2bisacsh
082	0	4	_a616.8 _223
245	1	0	_aInflammatory Disorders of the Nervous System _h[electronic resource] : _bPathogenesis, Immunology, and Clinical Management / _cedited by Alireza Minagar, J. Steven Alexander.
264		1	_aTotowa, NJ : _bHumana Press, _c2005.
300			_bonline resource.
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
347			_atext file _bPDF _2rda
490	1		_aCurrent Clinical Neurology
505	0		_aEndothelial Cell-Leukocyte Interactions During CNS Inflammation -- Multiple Sclerosis -- Cytokines and Brain -- Chemokines and Central Nervous System Disorders -- Circulating Cell-Derived Microparticles in Thrombotic and Inflammatory Disorders -- Multiple Sclerosis -- Neuroprotective Effects of Interferon-? in Multiple Sclerosis -- Acute Disseminated Encephalomyelitis -- Ingested Type I Interferon in Experimental Autoimmune Encephalomyelitis -- Neuromyelitis Optica -- Transverse Myelitis -- Optic Neuritis -- Central Nervous System Vasculitis -- Neurosarcoidosis -- Neuropsychiatric SLE -- Gene Expression in HIV-Associated Dementia -- Human T-Lymphotropic Virus-Associated Neurological Disorders -- West Nile Virus Infection of the Nervous System.
520			_aNow well recognized, the critical role of the inflammatory response in the pathophysiology of peripheral and central neurological disorders, including Alzheimer's and Parkinson's diseases, is today the subject of intense investigation at the molecular level. In Inflammatory Disorders of the Nervous System: Pathogenesis, Immunology, and Clinical Management, a panel of influential basic scientists review in detail the fundamental biological principles underlying the more common inflammatory disorders of the nervous system. The authors provide extensive updates on the latest findings concerning the mechanisms of inflammation and introduce such new concepts and methodologies as "endothelial and leukocyte microparticles" and "gene microarray technology" to help explain important links between the central nervous system (CNS) and general inflammatory processes. Among the diseases examined from an inflammatory perspective are multiple sclerosis, acute disseminated encephalomyelitis, optic neuritis, transverse myelitis, CNS vasculitis, neuropsychiatric systemic lupus erythematosis, Alzheimer's disease, and Parkinson's disease. The role of the immune system in neuroinflammation is also explored in such disorders as neurosarcoidosis, HIV-associated dementia, and HTLV-associated neurological disorders. Cutting-edge and authoritative, Inflammatory Disorders of the Nervous System: Pathogenesis, Immunology, and Clinical Management offers basic research and clinical scientists an illuminating introduction to the new world of inflammatory CNS conditions and the emerging diagnostic and therapeutic opportunities they provide.
650		0	_aMedicine.
650		0	_aNeurology.
650	1	4	_aMedicine & Public Health.
650	2	4	_aNeurology.
700	1		_aMinagar, Alireza. _eeditor.
700	1		_aAlexander, J. Steven. _eeditor.
710	2		_aSpringerLink (Online service)
773	0		_tSpringer eBooks
776	0	8	_iPrinted edition: _z9781588294241
830		0	_aCurrent Clinical Neurology
856	4	0	_uhttp://dx.doi.org/10.1385/1592599052
912			_aZDB-2-SME
950			_aMedicine (Springer-11650)
999			_c500782 _d500782