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001 978-1-59259-900-4
003 DE-He213
005 20161121230555.0
007 cr nn 008mamaa
008 100301s2005 xxu| s |||| 0|eng d
020 _a9781592599004
_9978-1-59259-900-4
024 7 _a10.1385/1592599001
_2doi
050 4 _aRC648-665.2
072 7 _aMJG
_2bicssc
072 7 _aMED027000
_2bisacsh
082 0 4 _a616.4
_223
245 1 0 _aStem Cells in Endocrinology
_h[electronic resource] /
_cedited by Linda B. Lester.
264 1 _aTotowa, NJ :
_bHumana Press,
_c2005.
300 _aXIV, 274 p.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aContemporary Endocrinology
505 0 _aBasic Stem Cell Biology -- Embryonic Stem Cells -- Germ Line Stem Cells -- Umbilical Cord Stem Cells -- Differentiation Potential of Adult Stem Cells -- Growth Conditions for Primate vs Murine Embryonic Stem Cells -- Translational Research -- Islet Precursor Cells in Adult Pancreatic Islets -- Transcription Factor-Directed Differentiation of Stem Cells Along an Endocrine Lineage -- Generation of Islet-Like Structures From ES Cells -- The Therapeutic Potential of Liver Repopulation for Metabolic or Endocrine Disorders -- The Manipulation of Mesenchymal Stem Cells for Bone Repair -- Spermatogenesis From Transplanted Spermatogenic Stem Cells -- Hematopoietic Stem Cell Transplant in the Treatment of Autoimmune Endocrine Disease -- Preclinical Trials for Stem Cell Therapy.
520 _aStem cell research can not only develop potential sources of cells for endocrine therapy, but can also allow the study of organ development ex vivo using isolated and defined stem cell precursors. In Stem Cells in Endocrinology, leading stem cell biologists and developmental endocrinologists critically review both cutting-edge approaches to stem cell biology and the application of stem cells to endocrine diseases, including diabetes, infertility, and liver-associated metabolic disorders. The authors discuss current research to modify stem cells, develop an endocrine-like cell, and use adult bone marrow stem cells to treat autoimmune diseases, including endocrine-based autoimmune diseases. Topics of interest include a review of all stem cell subtypes and their characteristics, approaches to promoting endocrine development from stem cells, and evidence for endocrine cell function from stem cells. The authors also outline how best to develop preclinical studies that will determine the safety and efficacy of stem cell therapies for endocrine disorders. Background chapters provide a basic understanding of stem cell biology and introduce all major types of stem cells, including embryonic, adult, cord blood, and germ line. State of the art and forward looking, Stem Cells in Endocrinology offers the basic and clinician scientist an authoritative evaluation of all aspects of how stem cells might be used to create endocrine cells and to treat such diseases as type 1 diabetes.
650 0 _aMedicine.
650 0 _aEndocrinology.
650 1 4 _aMedicine & Public Health.
650 2 4 _aEndocrinology.
700 1 _aLester, Linda B.
_eeditor.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9781588294074
830 0 _aContemporary Endocrinology
856 4 0 _uhttp://dx.doi.org/10.1385/1592599001
912 _aZDB-2-SME
950 _aMedicine (Springer-11650)
999 _c500779
_d500779