000			03831nam a22004335i 4500
001			978-1-59259-855-7
003			DE-He213
005			20161121230554.0
007			cr nn 008mamaa
008			100301s2005 xxu| s |||| 0|eng d
020			_a9781592598557 _9978-1-59259-855-7
024	7		_a10.1385/1592598552 _2doi
050		4	_aRC346-429.2
072		7	_aMJN _2bicssc
072		7	_aMED056000 _2bisacsh
082	0	4	_a616.8 _223
245	1	0	_aMultiple Sclerosis _h[electronic resource] : _bEtiology, Diagnosis, and New Treatment Strategies / _cedited by Michael J. Olek.
264		1	_aTotowa, NJ : _bHumana Press, _c2005.
300			_bonline resource.
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
347			_atext file _bPDF _2rda
490	1		_aCurrent Clinical Neurology
505	0		_aSigns and Symptoms of Multiple Sclerosis -- Differential Diagnosis, Clinical Features, and Prognosis of Multiple Sclerosis -- Role of Magnetic Resonance Imaging in the Diagnosis and Prognosis of Multiple Sclerosis -- Cognitive Dysfunction in Multiple Sclerosis -- Multiple Sclerosis, Genetics, and Autoimmunity -- B-Cell Immunity in Multiple Sclerosis -- Multiple Sclerosis -- Pregnancy and Multiple Sclerosis -- Treatment of Progressive Multiple Sclerosis -- Cyclophosphamide Therapy for Multiple Sclerosis -- Repair and Neuroprotective Strategies in Multiple Sclerosis -- Future Therapies for Multiple Sclerosis.
520			_aThe recent explosion of new information about the pathology, pathophysiology, clinical classification, imaging, and treatment of multiple sclerosis (MS) has dramatically opened the way to a deeper understanding of the disease and a more effective therapeutic landscape for patients. In Multiple Sclerosis: Etiology, Diagnosis, and New Treatment Strategies, leading MS physicians synthesize current concepts about the evaluation, treatment, and future directions in MS. On the evaluation side, the authors review the use of magnetic resonance imaging (MRI), magnetic resonance spectroscopy, functional MRI, and three-dimensional MRI, and consider the rapidly developing body of pathologic information they have yielded. On the treatment side, the focus is on recently approved medications (Novantrone), new indications for medications (CHAMPS Trial), medications in development (Oral Interferon Tau, Oral Copaxone, and Oral Cellcept), immunosuppressive therapy for both progressive disease and symptomatic therapy; the current medications for treating relapsing-remitting MS (Avonex, Betaseron, and Copaxone) are also discussed. For future directions, the authors present the current best thinking, as well as the latest discoveries in immunology relating to MS, including groundbreaking B-cell research, its applications to specific immunotherapies, and the use of immune markers for tracking the disease. Additional chapters cover the mechanism and application of myelin repair, bone marrow transplantation, combination therapy, and specific immunomodulatory treatments. Comprehensive and up-to-date, Multiple Sclerosis: Etiology, Diagnosis, and New Treatment Strategies reviews all the current immunological, neuropsychological, imaging, and pregnancy issues associated with MS and shows how each is contributing to the still ongoing development of more efficacious therapies.
650		0	_aMedicine.
650		0	_aNeurology.
650	1	4	_aMedicine & Public Health.
650	2	4	_aNeurology.
700	1		_aOlek, Michael J. _eeditor.
710	2		_aSpringerLink (Online service)
773	0		_tSpringer eBooks
776	0	8	_iPrinted edition: _z9781588290335
830		0	_aCurrent Clinical Neurology
856	4	0	_uhttp://dx.doi.org/10.1385/1592598552
912			_aZDB-2-SME
950			_aMedicine (Springer-11650)
999			_c500753 _d500753