000			02887nam a22005175i 4500
001			978-0-387-26274-1
003			DE-He213
005			20161121230552.0
007			cr nn 008mamaa
008			100301s2005 xxu| s |||| 0|eng d
020			_a9780387262741 _9978-0-387-26274-1
024	7		_a10.1007/b106814 _2doi
050		4	_aRC648-665.2
072		7	_aMJG _2bicssc
072		7	_aMED027000 _2bisacsh
082	0	4	_a616.4 _223
245	1	4	_aThe Growth Hormone/Insulin-Like Growth Factor Axis During Development _h[electronic resource] / _cedited by Isabel Varela-Nieto, Julie A. Chowen.
264		1	_aBoston, MA : _bSpringer US, _c2005.
300			_aVIII, 421 p. _bonline resource.
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
347			_atext file _bPDF _2rda
490	1		_aAdvances in Experimental Medicine and Biology, _x0065-2598 ; _v567
505	0		_aBasic Physiology of the Growth Hormone/Insulin-Like Growth Factor Axis -- Experimental Models for Understanding the Role of Insulin-like Growth Factor-I and Its Receptor During Development -- Insulin-like Growth Factor Binding Proteins in Development -- Growth Hormone, Insulin-like Growth Factors and the Female Reproductive System -- Skeletal Muscle -- Cardiovascular and Respiratory Systems -- Hematopoiesis -- Brain Development -- Regulation of Vertebrate Sensory Organ Development: A Scenario for Growth Hormone and Insulin-Like Growth Factors Action -- Role of Insulin-Like Growth Factors in Neuronal Plasticity and Neuroprotection -- Aging and Life Span -- Interactions of Insulin-Like Growth Factor-I and Estrogen in the Brain -- Cancer -- Genetic Basis of Proportional Short Stature -- Future Perspectives.
520			_aInsulin-like growth factor (IGF)-I is a widely expressed growth factor with diverse effects on many tissues throughout development and in adult life. The purpose of this work is to provide detailed and updated information on the role of the growth hormone (GH)-IGF axis in fetal and postnatal development, as well as its physiological functions and implications in pathology.
650		0	_aMedicine.
650		0	_aMaternal and child health services.
650		0	_aDiabetes.
650		0	_aEndocrinology.
650		0	_aNeurology.
650	1	4	_aMedicine & Public Health.
650	2	4	_aEndocrinology.
650	2	4	_aNeurology.
650	2	4	_aDiabetes.
650	2	4	_aMaternal and Child Health.
700	1		_aVarela-Nieto, Isabel. _eeditor.
700	1		_aChowen, Julie A. _eeditor.
710	2		_aSpringerLink (Online service)
773	0		_tSpringer eBooks
776	0	8	_iPrinted edition: _z9780387251196
830		0	_aAdvances in Experimental Medicine and Biology, _x0065-2598 ; _v567
856	4	0	_uhttp://dx.doi.org/10.1007/b106814
912			_aZDB-2-SME
950			_aMedicine (Springer-11650)
999			_c500693 _d500693