| 000 | 02895nam a22004335i 4500 | ||
|---|---|---|---|
| 001 | 978-0-387-25575-0 | ||
| 003 | DE-He213 | ||
| 005 | 20161121230551.0 | ||
| 007 | cr nn 008mamaa | ||
| 008 | 100301s2005 xxu| s |||| 0|eng d | ||
| 020 |
_a9780387255750 _9978-0-387-25575-0 |
||
| 024 | 7 |
_a10.1007/b135603 _2doi |
|
| 050 | 4 | _aRC681-688.2 | |
| 072 | 7 |
_aMJD _2bicssc |
|
| 072 | 7 |
_aMED010000 _2bisacsh |
|
| 082 | 0 | 4 |
_a616.12 _223 |
| 245 | 1 | 0 |
_aMitochondria and the Heart _h[electronic resource] / _cedited by José Marín-García. |
| 264 | 1 |
_aBoston, MA : _bSpringer US, _c2005. |
|
| 300 |
_aXVIII, 400 p. _bonline resource. |
||
| 336 |
_atext _btxt _2rdacontent |
||
| 337 |
_acomputer _bc _2rdamedia |
||
| 338 |
_aonline resource _bcr _2rdacarrier |
||
| 347 |
_atext file _bPDF _2rda |
||
| 490 | 1 |
_aDevelopments in Cardiovascular Medicine, _x0166-9842 ; _v256 |
|
| 505 | 0 | _aAn Introduction to Mitochondria and the Heart -- Mitochondrial Bioenergetics in the Heart -- Heart Mitochondrial Biogenesis -- ROS Generation, Antioxidants, and Cell Death -- Myocardial Ischemia and Cardioprotection -- Mitochondria Dysfunction in Cardiomyopathy and Heart Failure -- Fatty Acid and Glucose Metabolism in Cardiac Disease -- Mitochondria in Pediatric Cardiology -- Mitochondria and the Aging Heart -- Heart Mitochondria Signaling Pathways -- Treatment of Mitochondrial-Based Cardiac Diseases. Targeting the Organelle -- Future Frontiers in Mitochondrial Cardiac Biology. | |
| 520 | _aThe function of the heart is highly dependent on oxidative energy that is generated in mitochondria. Defects in mitochondrial structure and function can be found in association with cardiovascular diseases. Mitochondria and the Heart discusses the role that mitochondria plays in cardiovascular disease, including biogenesis and function of cardiac mitochondria during normal growth, development and aging. In addition, nonbioenergetic, biogenesis and degradation pathways are explored. Understanding these pathways and the effects that mitochondrial defects have in cardiac pathology is extremely important in establishing the diagnosis and treatment of mitochondrial-based cardiac diseases. José Marín-García is affiliated with The Molecular Cardiology and Neuromuscular Institute, Highland Park, New Jersey and the Department of Physiology & Biophysics, UMDNJ – Robert Wood Johnson Medical School, Piscataway, New Jersey. . | ||
| 650 | 0 | _aMedicine. | |
| 650 | 0 | _aCardiology. | |
| 650 | 1 | 4 | _aMedicine & Public Health. |
| 650 | 2 | 4 | _aCardiology. |
| 700 | 1 |
_aMarín-García, José. _eeditor. |
|
| 710 | 2 | _aSpringerLink (Online service) | |
| 773 | 0 | _tSpringer eBooks | |
| 776 | 0 | 8 |
_iPrinted edition: _z9780387255743 |
| 830 | 0 |
_aDevelopments in Cardiovascular Medicine, _x0166-9842 ; _v256 |
|
| 856 | 4 | 0 | _uhttp://dx.doi.org/10.1007/b135603 |
| 912 | _aZDB-2-SME | ||
| 950 | _aMedicine (Springer-11650) | ||
| 999 |
_c500687 _d500687 |
||