Technetium-99m Pharmaceuticals : Preparation and Quality Control in Nuclear Medicine /
Contributor(s): Zolle, Ilse [editor.] | SpringerLink (Online service).
Material type:
BookPublisher: Berlin, Heidelberg : Springer Berlin Heidelberg, 2007.Description: XX, 345 p. 66 illus., 1 illus. in color. online resource.Content type: text Media type: computer Carrier type: online resourceISBN: 9783540339908.Subject(s): Medicine | Radiology | Nuclear medicine | Medicine & Public Health | Imaging / Radiology | Nuclear MedicineDDC classification: 616.0757 Online resources: Click here to access online | Item type | Current location | Call number | Status | Date due | Barcode | Item holds |
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E books
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PK Kelkar Library, IIT Kanpur | Available | EBK3703 |
I -- Drug Safety -- Technetium in Medicine -- Stannous Chloride in the Preparation of 99mTc Pharmaceuticals -- Quality Assurance of Radiopharmaceuticals -- Performance and Quality Control of the 99Mo/99mTc Generator -- Preparation of Technetium 99mTc Pharmaceuticals -- Lyophilization Technique for Preparing Radiopharmaceutical Kits -- Cellular Labeling with 99mTc Chelates: Relevance of In Vitro and In Vivo Viability Testing -- Quality Control Methods of 99mTc Pharmaceuticals -- Other Technetium Isotopes: 94mTc as a Potential Substitute in Positron Emission Tomography Investigations -- The Rules Governing Medicinal Products for Human Use in the European Union -- II -- Monographs of 99mTc Pharmaceuticals.
This textbook gives an account of the accomplishments related to the development of 99mTc-radiopharmaceuticals and their application in diagnostic nuclear medicine. Since radioactive drug development is a multi-disciplinary task, experts working in nuclear medicine and research institutions have contributed valuable information concerning the preparation with sterile kits, methods of quality control, and the use of 99mTc-radiopharmaceuticals in patients. In addition, the legal aspects governing production and clinical application are also considered. Section 1 contains basic principles and methods used for analysis. Special emphasis is given to the analytical methods verifying pharmaceutical quality. Section 2 contains monographs of 99mTc-radiopharmaceuticals used in nuclear medicine. Each monograph includes information on the chemistry, formulation, commercial products and trade names, factors affection in-vivo performance, clinical information on pharmacokinetics, as well as details concerning the clinical application and the radiation dose to patients. This book can serve for daily practice in nuclear medicine, serving as a reference source as well as a teaching tool.
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