Contrast Agent Properties and Technical Aspects -- MRI Contrast Media — Introduction and Basic Properties of the Blood Pool Agent Gadofosveset (Vasovist®) -- Technical Aspects of Contrast Enhanced MRA — First Pass and Steady State -- Safety and Efficacy -- Risks and Safety Issues Related to Radiological Imaging, in Particular MRI -- Summary of Safety of Vasovist® at 0.03 mmol/kg Body Weight Dose — Clinical Data -- Efficacy of Vasovist®: Overview of the Clinical Development Program -- Blood Pool Agents in MRA: Indications, Clinical Applications and Benefits -- Head and Neck MRA -- Pulmonary MRA -- Abdominal MRA -- MRA of the Peripheral Vasculature -- Magnetic Resonance Venography -- Whole-body MRA -- Endoleak Imaging -- Gastrointestinal Bleeding -- New Horizons in Vascular Diagnostics -- Vasovist® for Imaging Ischemic and Congenital Heart Disease -- Vasovist® in Brain Tumor Imaging -- Vasovist® in Lymph Node Imaging: Present Status and Future Development -- Vasovist® for Breast Cancer Recognition -- Vasovist® for Multiple Sclerosis Recognition -- Interventional MR Imaging -- Vasovist® in Lymphography -- Image Processing -- Image Post-processing of Blood Pool MR Angiograms -- Pharmacoeconomic Impact -- Health Economic Benefits of Vasovist® -- Patient Management and Referrals: The Impact of High-resolution Steady state MRA with Vasovist®.

Clinical Blood Pool MR Imaging »This excellent treatise on Vasovist® created by a team of exceptional faculty who are pioneers in MR Angiography covers the basic techniques, safety, efficacy, image processing and pharmaco-economic details to successfully implement a new level of MRA image quality with this new contrast agent.« Martin Prince, Cornell University, New York »The editors and authors have made groundbreaking contributions towards establishing MR angiography in various investigative settings, rendering it more precise and applying it for diverse indications. The work presented here is founded upon the extensive experience of the editors, as well as the broad range of experience from other scientific working groups.« Maximilian Reiser, Ludwig Maximilian University, Munich Vasovist® (Gadofosveset), worldwide the first blood pool agent, has only recently become available for clinical use, but has already gained wide acceptance as a tool to improve magnetic resonance angiography. This book presents the first in-depth introduction to the basic physicochemical aspects of the agent, the application of Vasovist® in clinical MRA, as well as potential clinical applications beyond MRA and patient management-related aspects. The first part of the book explains basic and technical properties of the agent and the differences of Vasovist® compared to currently available extracellular agents. The second part contains detailed chapters on safety and efficacy. In the third part the focus is on MR angiographic applications, and in the fourth part of the book potential clinical fields beyond MRA are explored. All clinical chapters feature ready-to-use clinical protocols and a series of take home messages that concisely summarize the current role of blood pool imaging for each specific indication.