Mode of access: World Wide Web.

System requirements: Adobe Acrobat reader.

Part of: Synthesis digital library of engineering and computer science.

Series from website.

Includes bibliographical references.

1. Introduction -- Chapter summary -- Background -- Bone tissue engineering -- Biomechanics vs. bone tissue engineering -- Objectives and scopes -- Organization of the monograph -- Bibliography -- 2. Bone composition and structure -- Chapter summary -- Introduction -- Bone architecture -- Ultrastructure/composition of bone -- Differences between species -- Summary -- Bibliography -- 3. Current mechanical test methodologies -- Chapter summary -- Introduction -- Definition of mechanical properties -- Mechanical testing of bulk bone tissues -- Micro-mechanical testing methodologies -- Nano-indentation methodologies -- Bibliography -- 4. Mechanical behavior of bone -- Chapter summary -- Introduction -- Mechanical properties of whole bone -- Mechanical properties of bone at the macroscopic level -- Mechanical properties of bone at the microscopic level -- Mechanical properties of bone at the sub-microscopic level -- Mechanical properties of hydroxyapatite and collagen -- Physiological response of bone to functional loading -- Concluding remarks -- Bibliography -- 5. Structure and properties of scaffolds for bone tissue regeneration -- Chapter summary -- Introduction -- Synthetic polymers -- Bioceramics -- Metals -- Structural requirements for functional scaffolds -- The balance between scaffold degradation and tissue regeneration -- Determinants of degradation -- Conclusion -- Bibliography.

6. Mechanical and structural evaluation of repair/tissue engineered bone -- Chapter summary -- Introduction -- In vitro biomechanical evaluation of fracture repair -- In vivo stiffness monitoring of healing bone -- Non-invasive measurement of fracture healing -- Numerical evaluation of fracture healing -- Summary -- Bibliography -- 7. Mechanical and structural properties of tissues engineered/repair bone -- Chapter summary -- Introduction -- Biological stages of fracture healing -- Intramembranous bone formation in the critical sized defect -- Biomechanical properties of repair/tissue engineered bone -- Biomechanical properties of tissue engineered bone -- Summary -- Bibliography -- 8. Current issues of biomechanics in bone tissue engineering -- Chapter summary -- Introduction -- Ideal scaffold system for bone tissue engineering -- Bioreactor: biomimetic environment for bone formation -- Mechanobiology in bone tissue engineering -- Summary -- Bibliography -- Authors' biographies.

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This eight-chapter monograph intends to present basic principles and applications of biomechanics in bone tissue engineering in order to assist tissue engineers in design and use of tissue-engineered products for repair and replacement of damaged/deformed bone tissues. Briefly, Chapter 1 gives an overall review of biomechanics in the field of bone tissue engineering. Chapter 2 provides detailed information regarding the composition and architecture of bone. Chapter 3 discusses the current methodologies for mechanical testing of bone properties (i.e., elastic, plastic, damage/fracture, viscoelastic/ viscoplastic properties). Chapter 4 presents the current understanding of the mechanical behavior of bone and the associated underlying mechanisms. Chapter 5 discusses the structure and properties of scaffolds currently used for bone tissue engineering applications. Chapter 6 gives a brief discussion of current mechanical and structural tests of repair/tissue engineered bone tissues. Chapter 7 summarizes the properties of repair/tissue engineered bone tissues currently attained. Finally, Chapter 8 discusses the current issues regarding biomechanics in the area of bone tissue engineering.

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Title from PDF t.p. (viewed on February 15, 2010).