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Toll-Like Receptors (TLRs) and Innate Immunity

Contributor(s): Bauer, Stefan [editor.] | Hartmann, Gunther [editor.] | SpringerLink (Online service).
Material type: materialTypeLabelBookSeries: Handbook of Experimental Pharmacology: 183Publisher: Berlin, Heidelberg : Springer Berlin Heidelberg, 2008.Description: XII, 240 p. 25 illus., 4 illus. in color. online resource.Content type: text Media type: computer Carrier type: online resourceISBN: 9783540721673.Other title: With contributions by numerous experts.Subject(s): Medicine | Immunology | Medical microbiology | Pharmacology | Biomedicine | Pharmacology/Toxicology | Immunology | Medical MicrobiologyDDC classification: 615 Online resources: Click here to access online
Contents:
Toll-Like Receptors (TLRs) and Their Ligands -- Signalling of Toll-Like Receptors -- TLR9-Mediated Recognition of DNA -- RNA Recognition via TLR7 and TLR8 -- Fungal Recognition by TLR2 and Dectin-1 -- Heat Shock Proteins and Toll-Like Receptors -- Nucleic Acid Recognition Receptors in Autoimmunity -- Dendritic Cell Subsets and Toll-Like Receptors -- Structure of Toll-Like Receptors -- Toll-Like Receptor-Agonists in the Treatment of Skin Cancer: History, Current Developments and Future Prospects -- Vaccination with Messenger RNA (mRNA).
In: Springer eBooksSummary: Overall recent research on TLRs has led to tremendous increase in our understanding of early steps in pathogen recognition and will presumably lead to potent TLR targeting therapeutics in the future. This book reviews and highlights our recent understanding on the function and ligands of TLRs as well as their role in autoimmunity, dendritic cell activation and target structures for therapeutic intervention.
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Item type Current location Call number Status Date due Barcode Item holds
E books E books PK Kelkar Library, IIT Kanpur
Available EBK4355
Total holds: 0

Toll-Like Receptors (TLRs) and Their Ligands -- Signalling of Toll-Like Receptors -- TLR9-Mediated Recognition of DNA -- RNA Recognition via TLR7 and TLR8 -- Fungal Recognition by TLR2 and Dectin-1 -- Heat Shock Proteins and Toll-Like Receptors -- Nucleic Acid Recognition Receptors in Autoimmunity -- Dendritic Cell Subsets and Toll-Like Receptors -- Structure of Toll-Like Receptors -- Toll-Like Receptor-Agonists in the Treatment of Skin Cancer: History, Current Developments and Future Prospects -- Vaccination with Messenger RNA (mRNA).

Overall recent research on TLRs has led to tremendous increase in our understanding of early steps in pathogen recognition and will presumably lead to potent TLR targeting therapeutics in the future. This book reviews and highlights our recent understanding on the function and ligands of TLRs as well as their role in autoimmunity, dendritic cell activation and target structures for therapeutic intervention.

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