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Recombination and Meiosis : Models, Means, and Evolution /

Contributor(s): Egel, Richard [editor.] | Lankenau, Dirk-Henner [editor.] | SpringerLink (Online service).
Material type: materialTypeLabelBookSeries: Genome Dynamics and Stability: 3Publisher: Berlin, Heidelberg : Springer Berlin Heidelberg, 2008.Description: XXI, 390 p. online resource.Content type: text Media type: computer Carrier type: online resourceISBN: 9783540689843.Subject(s): Life sciences | Human genetics | Biochemistry | Cell biology | Plant genetics | Animal genetics | Life Sciences | Cell Biology | Biochemistry, general | Animal Genetics and Genomics | Human Genetics | Plant Genetics & GenomicsDDC classification: 571.6 Online resources: Click here to access online
Contents:
Evolution of Models of Homologous Recombination -- Searching for Homology by Filaments of RecA-Like Proteins -- Biochemistry of Meiotic Recombination: Formation, Processing, and Resolution of Recombination Intermediates -- Meiotic Chromatin: The Substrate for Recombination Initiation -- Meiotic Recombination in Schizosaccharomyces pombe: A Paradigm for Genetic and Molecular Analysis -- Nuclear Movement Enforcing Chromosome Alignment in Fission Yeast—Meiosis Without Homolog Synapsis -- On the Origin of Meiosis in Eukaryotic Evolution: Coevolution of Meiosis and Mitosis from Feeble Beginnings -- The Legacy of the Germ Line – Maintaining Sex and Life in Metazoans: Cognitive Roots of the Concept of Hierarchical Selection -- Lessons to Learn from Ancient Asexuals.
In: Springer eBooksSummary: Once per life cycle, mitotic nuclear divisions are replaced by meiosis I and II—reducing chromosome number from the diploid level to a haploid genome and recombining chromosome arms by crossing-over. In animals, all this happens during formation of eggs and sperm—in yeasts before spore formation. The mechanisms of reciprocal exchange at crossover/chiasma sites are central to mainstream meiosis. To initiate the meiotic exchange of DNA, surgical cuts are made as a form of calculated damage that subsequently is repaired by homologous recombination. These key events are accompanied by ancillary provisions at the level of chromatin organization, sister chromatid cohesion and differential centromere connectivity. Great progress has been made in recent years in our understanding of these mechanisms. Questions still open primarily concern the placement of and mutual coordination between neighboring crossover events. Of overlapping significance, this book features two comprehensive treatises of enzymes involved in meiotic recombination, as well as the historical conceptualization of meiotic phenomena from genetical experiments. More specifically, these mechanisms are addressed in yeasts as unicellular model eukaryotes. Furthermore, evolutionary subjects related to meiosis are treated.
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Item type Current location Call number Status Date due Barcode Item holds
E books E books PK Kelkar Library, IIT Kanpur
Available EBK4327
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Evolution of Models of Homologous Recombination -- Searching for Homology by Filaments of RecA-Like Proteins -- Biochemistry of Meiotic Recombination: Formation, Processing, and Resolution of Recombination Intermediates -- Meiotic Chromatin: The Substrate for Recombination Initiation -- Meiotic Recombination in Schizosaccharomyces pombe: A Paradigm for Genetic and Molecular Analysis -- Nuclear Movement Enforcing Chromosome Alignment in Fission Yeast—Meiosis Without Homolog Synapsis -- On the Origin of Meiosis in Eukaryotic Evolution: Coevolution of Meiosis and Mitosis from Feeble Beginnings -- The Legacy of the Germ Line – Maintaining Sex and Life in Metazoans: Cognitive Roots of the Concept of Hierarchical Selection -- Lessons to Learn from Ancient Asexuals.

Once per life cycle, mitotic nuclear divisions are replaced by meiosis I and II—reducing chromosome number from the diploid level to a haploid genome and recombining chromosome arms by crossing-over. In animals, all this happens during formation of eggs and sperm—in yeasts before spore formation. The mechanisms of reciprocal exchange at crossover/chiasma sites are central to mainstream meiosis. To initiate the meiotic exchange of DNA, surgical cuts are made as a form of calculated damage that subsequently is repaired by homologous recombination. These key events are accompanied by ancillary provisions at the level of chromatin organization, sister chromatid cohesion and differential centromere connectivity. Great progress has been made in recent years in our understanding of these mechanisms. Questions still open primarily concern the placement of and mutual coordination between neighboring crossover events. Of overlapping significance, this book features two comprehensive treatises of enzymes involved in meiotic recombination, as well as the historical conceptualization of meiotic phenomena from genetical experiments. More specifically, these mechanisms are addressed in yeasts as unicellular model eukaryotes. Furthermore, evolutionary subjects related to meiosis are treated.

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