Management of Peritoneal Surface Malignancy: A Short History -- The Natural History of Free Cancer Cells in the Peritoneal Cavity -- Pathological Evaluation and Implications of Serosal Involvement in Gastrointestinal Cancer -- Principles of Perioperative Intraperitoneal Chemotherapy for Peritoneal Carcinomatosis -- Experimental and Pharmacokinetic Studies in Intraperitoneal Chemotherapy: From Laboratory Bench to Bedside -- Technology for the Delivery of Hyperthermic Intraoperative Intraperitoneal Chemotherapy: A Survey of Techniques -- Adjuvant Intraperitoneal Chemotherapy: A Review -- Clinical Research Methodology in Peritoneal Surface Oncology: A Difficult Challenge -- Lessons Learnt from Clinical Trials in Peritoneal Surface Oncology: Colorectal Carcinomatosis -- Experimental Models and Questions in Basic Science Research for Pseudomyxoma Peritonei -- Peritoneal Carcinomatosis of Colorectal Origin: Recent Advances and Future Evolution Toward a Curative Treatment -- Pathologic Characterization and Differential Diagnosis of Malignant Peritoneal Mesothelioma -- Advances in Clinical Research and Management of Diffuse Peritoneal Mesothelioma -- Advances in the Management of Gastric Cancer with Peritoneal Dissemination -- Intraperitoneal Chemotherapy in the Management of Ovarian Cancer.

S. Gonz�lez-Moreno (Ed. ) Advances in Peritoneal Surface Oncology With 45 Figures in 57 Separate Illustrations, 12 in Color and 19 Tables 123 IV Preface Santiago Gonz�lez-Moreno, MD, PhD Department of Surgical Oncology Centro Oncol�gico MD Anderson International Espa�a Calle G�mez Hemans 2 28033 Madrid Spain sgonzalez@mdanderson. es Library of Congress Control Number: 2006937141 ISSN 0080-0015 ISBN 978-3-540-30759-4 Springer Berlin Heidelberg New York This work is subject to copyright. All rights are reserved, whether the whole or part of the material is concerned, speci? ?cally the rights of translation, reprinting, reuse of illustrations, recitations, broadcasting, reproduction on micro? ?lm or in any other way, and storage in data banks. Duplication of this publication or parts thereof is permitted only under the provisions of the German Copyright Law of September 9, 1965, in its current version, and permission for use must always be obtained from Springer-Verlag. Violations are liable for prosecution under the German Copyright Law. Springer is part of Springer Science+Business Media http//www. springer. com Springer-Verlag Berlin Heidelberg 2007 Printed in Germany The use of general descriptive names, trademarks, etc. in this publication does not imply, even in the absence of a speci? ?c sta- ment, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. Product liability: The publishers cannot guarantee the accuracy of any information about dosage and application contained in this book. In every case the user must check such information by consulting the relevant literature. 0 Me