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Axonal Branching and Recovery of Coordinated Muscle Activity after Transection of the Facial Nerve in Adult Rats

By: Angelov, Doychin N [author.].
Contributor(s): Neiss, Wolfram F [author.] | Guntinas-Lichius, Orlando [author.] | Streppel, Michael [author.] | Wewetzer, Konstantin [author.] | SpringerLink (Online service).
Material type: materialTypeLabelBookSeries: Advances in Anatomy Embryology and Cell Biology: 180Publisher: Berlin, Heidelberg : Springer Berlin Heidelberg, 2005.Description: X, 132 p. 23 illus., 4 illus. in color. online resource.Content type: text Media type: computer Carrier type: online resourceISBN: 9783540299318.Subject(s): Medicine | Neurosciences | Biomedicine | NeurosciencesDDC classification: 612.8 Online resources: Click here to access online
Contents:
Outline of the General Neurobiological Problem -- The Perikarya Which Support Axonal Regrowth are Hyperexcitable -- Axonal Regrowth is Compromised by Ephaptic Cross-Talk Between the Branches -- Biological Significance of Axonal Branching -- Role of Cytoskeleton Reorganization During Axonal Branching -- The Individual Guidance Cues Promoting Reinnervation of Original Targets are Still Unknown -- Conclusion -- Outline of the Clinical Problem -- Questions Still Open -- Methodological Approach -- Materials and Methods -- First Set of Experiments: Attempts to Reduce Collateral Axonal Branching by Alterations of the Trigeminal Input to the Facial Perikarya -- Second Set of Experiments: Attempts to Reduce Collateral Axonal Branching at the Lesion Site -- Results -- First Set of Experiments: Influence of the Altered Afferent Input to Axotomized Facial Perikarya on the Quality of Reinnervation -- Second set of Experiments: Attempts to Reduce Collateral Axonal Branching at the Lesion Site -- Discussion -- The Combined Approach to Evaluate the Quality of Peripheral Nerve Regeneration -- Sensory-Motor Integrity as A Factor for Motor Regeneration -- Collateral Branching Versus Terminal Sprouting of Axons -- Prospects for the Future -- References -- Subject index.
In: Springer eBooksSummary: (folgt).
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Outline of the General Neurobiological Problem -- The Perikarya Which Support Axonal Regrowth are Hyperexcitable -- Axonal Regrowth is Compromised by Ephaptic Cross-Talk Between the Branches -- Biological Significance of Axonal Branching -- Role of Cytoskeleton Reorganization During Axonal Branching -- The Individual Guidance Cues Promoting Reinnervation of Original Targets are Still Unknown -- Conclusion -- Outline of the Clinical Problem -- Questions Still Open -- Methodological Approach -- Materials and Methods -- First Set of Experiments: Attempts to Reduce Collateral Axonal Branching by Alterations of the Trigeminal Input to the Facial Perikarya -- Second Set of Experiments: Attempts to Reduce Collateral Axonal Branching at the Lesion Site -- Results -- First Set of Experiments: Influence of the Altered Afferent Input to Axotomized Facial Perikarya on the Quality of Reinnervation -- Second set of Experiments: Attempts to Reduce Collateral Axonal Branching at the Lesion Site -- Discussion -- The Combined Approach to Evaluate the Quality of Peripheral Nerve Regeneration -- Sensory-Motor Integrity as A Factor for Motor Regeneration -- Collateral Branching Versus Terminal Sprouting of Axons -- Prospects for the Future -- References -- Subject index.

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