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Neuronal Input Pathways to the Brain’s Biological Clock and their Functional Significance

By: Hannibal, Jens [author.].
Contributor(s): Fahrenkrug, Jan [author.] | SpringerLink (Online service).
Material type: materialTypeLabelBookSeries: Advances in Anatomy Embryology and Cell Biology: 182Publisher: Berlin, Heidelberg : Springer Berlin Heidelberg, 2006.Description: X, 76 p. 22 illus., 13 illus. in color. online resource.Content type: text Media type: computer Carrier type: online resourceISBN: 9783540277897.Subject(s): Medicine | Biomedicine | Biomedicine generalDDC classification: 610 Online resources: Click here to access online
Contents:
Introduction -- The suprachiasmatic nucleus (SCN) -- The endogenous rhythm of the SCN -- The SCN molecular clock -- Photic regulation of the circadian rhythm -- Retinal input – Neuroanatomy -- Neurotransmitters in the RHT -- Glutamate and PACAP -- Other neurotransmitters of the RHT -- RHT neurotransmitter receptors in the SCN.-Melanopsin - an irradiance detecting photopigment of the RHT -- Retinal input - Physiology -- Non-photic regulation of the circadian rhythms -- Midbrain raphe input - Neuroanatomy -- 5-HT and regulation of the circadian system -- The intergeniculate leaflet and the geniculohypothalamic tract – neuroanatomy -- Effects of NPY on circadian rhythm during subjective day -- NPY modulates light-induced phase shift during subjective night -- Summary.
In: Springer eBooksSummary: Circadian rhythms are entrained daily by environmental photic and non-photic cues. The present review describes the anatomy and functional characteristics of the three major input pathways to the circadian clock mediating entrainment, the retino-hypothalamic tract (RHT), the geniculo-hypothalamic tract (GHT) and the midbrain raphe projection.
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Introduction -- The suprachiasmatic nucleus (SCN) -- The endogenous rhythm of the SCN -- The SCN molecular clock -- Photic regulation of the circadian rhythm -- Retinal input – Neuroanatomy -- Neurotransmitters in the RHT -- Glutamate and PACAP -- Other neurotransmitters of the RHT -- RHT neurotransmitter receptors in the SCN.-Melanopsin - an irradiance detecting photopigment of the RHT -- Retinal input - Physiology -- Non-photic regulation of the circadian rhythms -- Midbrain raphe input - Neuroanatomy -- 5-HT and regulation of the circadian system -- The intergeniculate leaflet and the geniculohypothalamic tract – neuroanatomy -- Effects of NPY on circadian rhythm during subjective day -- NPY modulates light-induced phase shift during subjective night -- Summary.

Circadian rhythms are entrained daily by environmental photic and non-photic cues. The present review describes the anatomy and functional characteristics of the three major input pathways to the circadian clock mediating entrainment, the retino-hypothalamic tract (RHT), the geniculo-hypothalamic tract (GHT) and the midbrain raphe projection.

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