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Epigenetics and Chromatin

Contributor(s): Jeanteur, Philippe [editor.] | SpringerLink (Online service).
Material type: materialTypeLabelBookSeries: Progress in Molecular and Subcellular Biology: 38Publisher: Berlin, Heidelberg : Springer Berlin Heidelberg, 2005.Description: XIII, 266 p. online resource.Content type: text Media type: computer Carrier type: online resourceISBN: 9783540273103.Subject(s): Life sciences | Biochemistry | Cell biology | Developmental biology | Evolutionary biology | Life Sciences | Biochemistry, general | Cell Biology | Evolutionary Biology | Developmental BiologyDDC classification: 572 Online resources: Click here to access online
Contents:
Chromatin Remodeling Factors and DNA Replication -- Epigenetic Inheritance of Chromatin States Mediated by Polycomb and Trithorax Group Proteins in Drosophila -- How to Pack the Genome for a Safe Trip -- Chromatin Modifications on the Inactive X Chromosome -- Chromatin Mechanisms in Drosophila Dosage Compensation -- DNA Methylation in Epigenetic Control of Gene Expression -- The Epigenetic Breakdown of Cancer Cells: From DNA Methylation to Histone Modifications -- Developmental Regulation of the ?-Globin Gene Locus -- Epigenetic Regulation of Mammalian Imprinted Genes: From Primary to Functional Imprints -- Seed Development and Genomic Imprinting in Plants.
In: Springer eBooksSummary: Epigenetics refers to heritable patterns of gene expression which do not depend on alterations of genomic DNA sequence. This book provides a state-of-the-art account of a few selected hot spots by scientists at the edge in this extremely active field. It puts special emphasis on two main streams of research. One is the role of post-translational modifications of proteins, mostly histones, on chromatin structure and accessibility. The other one deals with parental genomic imprinting, a process which allows to express a few selected genes from only one of the parental allele while extinguishing the other.
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Chromatin Remodeling Factors and DNA Replication -- Epigenetic Inheritance of Chromatin States Mediated by Polycomb and Trithorax Group Proteins in Drosophila -- How to Pack the Genome for a Safe Trip -- Chromatin Modifications on the Inactive X Chromosome -- Chromatin Mechanisms in Drosophila Dosage Compensation -- DNA Methylation in Epigenetic Control of Gene Expression -- The Epigenetic Breakdown of Cancer Cells: From DNA Methylation to Histone Modifications -- Developmental Regulation of the ?-Globin Gene Locus -- Epigenetic Regulation of Mammalian Imprinted Genes: From Primary to Functional Imprints -- Seed Development and Genomic Imprinting in Plants.

Epigenetics refers to heritable patterns of gene expression which do not depend on alterations of genomic DNA sequence. This book provides a state-of-the-art account of a few selected hot spots by scientists at the edge in this extremely active field. It puts special emphasis on two main streams of research. One is the role of post-translational modifications of proteins, mostly histones, on chromatin structure and accessibility. The other one deals with parental genomic imprinting, a process which allows to express a few selected genes from only one of the parental allele while extinguishing the other.

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