Fas Signaling
By: Wajant, Harald [author.].
Contributor(s): SpringerLink (Online service).
Material type:
BookSeries: Medical Intelligence Unit: Publisher: Boston, MA : Springer US, 2006.Description: VIII, 160 p. 32 illus., 4 illus. in color. online resource.Content type: text Media type: computer Carrier type: online resourceISBN: 9780387345734.Subject(s): Medicine | Immunology | Molecular biology | Oncology | Biomedicine | Immunology | Molecular Medicine | OncologyDDC classification: 616.079 Online resources: Click here to access online | Item type | Current location | Call number | Status | Date due | Barcode | Item holds |
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E books
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PK Kelkar Library, IIT Kanpur | Available | EBK2517 |
FasL and Fas -- FasL-Independent Activation of Fas -- Role of Ceramide in CD95 Signaling -- Regulation of Fas Signaling by FLIP Proteins -- Fas-Induced Necrosis -- Fas—More Than an Apoptosis Inducer -- Retrograde Fas Ligand Signaling -- FasL and Fas in Liver Homeostasis and Hepatic Injuries -- Fas-Activation, Development and Homeostasis of T Cells -- The FasL-Fas System in Disease and Therapy -- Tools for Activation and Neutralization of Fas Signaling.
Fas Signaling is focused on the signaling mechanisms and biology of the prototypic death receptor Fas, also called CD95 or APO-1. The chapters of this book cover, besides the well recognized apoptosis-related functions of Fas, its emerging role as a proinflammatory cytokine and as an inducer of alternative forms of cell death. Fas Signaling aims to provide the reader with an up-to-date survey of the various aspects of Fas biology and the open questions of the field are addressed. This title is intended for Ph.D and post-doctoral students starting to work in the field, but is also useful for everyone with an interest in the biology of this exciting molecule.
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