General Considerations I -- Anatomy and Physiology of the Thyroid Gland -- Epidemiology of Thyroid Cancer -- Molecular Pathogenesis of Thyroid Cancer -- Molecular Aspects of Thyroid Cancer in Children -- Oncogenes in Thyroid Cancer -- Apoptosis in Thyroid Cancer -- Radiation-Induced Thyroid Cancer -- Classification of Thyroid Malignancies -- Staging of Thyroid Cancer -- Thyroid Cancer in Children and Adolescents -- Recombinant Human Thyrotropin -- General Considerations II -- History of the Role of Nuclear Medicine in the Thyroid Gland and its Diseases -- Prophylaxis Against Radiation Exposure from Radioiodine -- Radioiodine Whole Body Imaging -- Primer and Atlas for the Interpretation of Radioiodine Whole-Body Scintigraphy -- False-Positive Radioiodine Scans in Thyroid Cancer -- The Thyroid Nodule -- The Thyroid Nodule -- Fine-Needle Aspiration -- Thyroid Nodules -- Radionuclide Imaging of Thyroid Nodules -- Ultrasonic Imaging of the Neck in Patients with Thyroid Cancer -- Thyroid Nodules and Cancer Risk -- Well-Differentiated Thyroid Cancer: Papillary Carcinoma -- Papillary Carcinoma -- Surgical Approach to Papillary Carcinoma -- Papillary Carcinoma -- Well-Differentiated Thyroid Cancer -- Prescribed Activity for Radioiodine Ablation -- Thyroid Remnant Radioiodine Ablation with Recombinant Human Thyrotropin -- Well-Differentiated Thyroid Cancer -- Follow-Up Strategy in Papillary Thyroid Cancer -- Levothyroxine Therapy and Thyrotropin Suppression -- Thyroglobulin and Thyroglobulin Antibodies -- Diagnosis of Recurrent Thyroid Cancer in Patients with Antithyroglobulin Antibodies -- Surveillance Radioiodine Whole-Body Scans -- Radionuclide Imaging and Treatment of Thyroid Cancer in Children -- Positron Emission Tomography in Well-Differentiated Thyroid Cancer -- Alternative Thyroid Imaging -- Stunning: Untoward Effect of 131I Thyroid Imaging Prior to Radioablation Therapy -- Stunning Is Not a Problem -- Stunning: Does it Exist? A Commentary -- Ultrasonic Imaging and Identification of Metastases in Cervical Lymph Nodes -- Magnetic Resonance Imaging and Computed Tomography of Thyroid Cancer -- Management of the Patients with Negative Radioiodine Scan and Elevated Serum Thyroglobulin -- Determinants of Prognosis in Papillary Thyroid Cancer -- Papillary Cancer -- Special Presentations of Thyroid Cancer in Pregnancy, Renal Failure, Thyrotoxicosis, and Struma Ovarii -- Thyroglossal Duct Carcinoma -- Well-Differentiated Thyroid Cancer -- Radiation and Radioactivity -- Radioiodine Treatment of Distant Metastases -- 131I Treatment of Metastatic Thyroid Carcinoma Following Preparation by Recombinant Human Thyrotropin -- Dosimetry -- Radioiodine Dosimetry with Recombinant Human Thyrotropin -- Use of Lithium as an Adjuvant to Radioiodine in the Treatment of Thyroid Cancer -- Side Effects of 131I for Ablation and Treatment of Well-Differentiated Thyroid Carcinoma -- External Radiation Therapy of Papillary Cancer -- Chemotherapy for Thyroid Cancer -- Chemotherapy of Differentiated Papillary or Follicular Thyroid Carcinoma -- Thyroid Carcinoma -- Adjunctive Local Approaches to Metastatic Thyroid Cancer -- Well-Differentiated Thyroid Cancer -- Follicular Thyroid Carcinoma -- Surgical Management of Follicular Cancer -- Pathology of Follicular Cancer -- H�rthle Cell Carcinoma -- Radionuclide Imaging, Ablation, and Treatment in Follicular Thyroid Carcinoma -- Follow-up Strategy in Follicular Thyroid Cancer -- PET in Follicular Cancer, Including H�rthle Cell Cancer -- Follicular Thyroid Cancer -- External Radiation Therapy of Follicular Carcinoma -- Determinants of Prognosis in Patients With Follicular Thyroid Cancer -- Variants of Thyroid Cancer -- Miscellaneous and Unusual Types of Thyroid Tumors -- Pathology of Miscellaneous and Unusual Cancers of the Thyroid -- Undifferentiated Tumors -- Clinical Aspects of Medullary Thyroid Carcinoma -- Pathology of Medullary Thyroid Cancer -- Medullary Carcinoma of the Thyroid -- Radionuclide Imaging of Medullary Carcinoma -- PET in Medullary Thyroid Cancer -- External Radiation Therapy of Medullary Cancer -- Medullary Carcinoma of the Thyroid -- Undifferentiated Tumors -- Thyroid Lymphoma -- Pathology of Lymphoma of the Thyroid -- FDG-PET Scanning in Lymphoma and Lymphoma of the Thyroid -- Undifferentiated Tumors -- Anaplastic Carcinoma -- Surgical Management of Anaplastic Thyroid Carcinoma -- Pathology of Anaplastic Carcinoma -- PET Scanning in Anaplastic Cancer of the Thyroid -- External Radiation Therapy of Anaplastic Thyroid Cancer -- Chemotherapy for Anaplastic Thyroid Cancer -- Anaplastic Carcinoma -- New Frontiers and Future Directions -- Advances in Radiation Therapy -- New Approaches in Nuclear Medicine for Thyroid Cancer -- Alternative Options and Future Directions for Thyroid Cancer Therapy -- Potential Approaches to Chemotherapy of Thyroid Cancer in the Future -- Resources for Patients with Thyroid Cancer -- Low Iodine Diets.

In a massive updating of the highly acclaimed Thyroid Cancer: A Comprehensive Guide to Clinical Management, Drs. Leonard Wartofsky, Douglas Van Nostrand, and an expert group of contributing authors present a wealth of new information and insights on every aspect of the etiology, pathogenesis, diagnosis, initial treatment, and long-term management of all varieties of thyroid cancer. Paramount to this new edition is a thorough treatment of the nuclear medical aspects of diagnosing and managing the thyroid cancer patient. This includes extensive discussion of isotopes, isotope uptake and scanning procedures, radioiodine ablation and dosimetry (with or without recombinant human TSH), stunning, octreotide and FDG-PET scanning, and various alternative imaging modalities. Additional highlights include management of the scan-negative and thyroglobulin-positive patient, ultrasound of the lymph nodes, local adjuncts to therapy of metastases, low iodine diets and cookbooks, future directions in therapy, and alternative therapies when traditional surgery and radioactive iodine fail. Encyclopedic and definitive, Thyroid Cancer: A Comprehensive Guide to Clinical Management, Second Edition, offers clinical endocrinologists, nuclear medicine physicians, pathologists, oncologists, endocrine surgeons, and internists an authoritative guide to the optimal diagnosis and treatment of thyroid cancer today. 0