| 000 -LEADER |
|---|
| fixed length control field |
02303 a2200349 4500 |
| 003 - CONTROL NUMBER IDENTIFIER |
|---|
| control field |
OSt |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
|---|
| control field |
20240304151124.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
|---|
| fixed length control field |
240227b xxu||||| |||| 00| 0 eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
|---|
| ISBN |
9783031424212 |
| 040 ## - CATALOGING SOURCE |
|---|
| Transcribing agency |
IIT Kanpur |
| 041 ## - LANGUAGE CODE |
|---|
| Language code of text/sound track or separate title |
eng |
| 082 ## - DEWEY DECIMAL CLASSIFICATION NUMBER |
|---|
| Classification number |
547 |
| Item number |
P943 v.123 |
| 245 ## - TITLE STATEMENT |
|---|
| Title |
Progress in the chemistry of organic natural products [V.123] |
| Statement of responsibility, etc |
Yoshiyasu Fukuyama, Miwa Kubo and Kenichi Harada ; edited by A. Douglas Kinghorn ...[et al.] |
| Remainder of title |
neurotrophic natural products |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT) |
|---|
| Name of publisher |
Springer |
| Year of publication |
2024 |
| Place of publication |
Switzerland |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Number of Pages |
ix, 473p |
| 440 ## - SERIES STATEMENT/ADDED ENTRY--TITLE |
|---|
| Title |
Progress in the chemistry of organic natural products |
| 490 ## - SERIES STATEMENT |
|---|
| Series statement |
/ edited by A. Douglas Kinghorn ...[et al.] |
| Volume number/sequential designation |
; v.123 |
| 520 ## - SUMMARY, ETC. |
|---|
| Summary, etc |
This book deals with neurotrophins (NGF, BDNF, NT3, NT4), which can decrease cell death, induce differentiation, as well as sustain the structure and function of neurons. This makes neurotrophins potential therapeutic agents for the treatment of neurodegenerative disorders. However, these proteins have so far been ineffective in clinical trials mostly because they cannot pass the blood-brain barrier owing to their high-molecular weights. Consequently, small molecules that mimic neurotrophins and stimulate the synthesis of endogenous neurotrophins or enhance their neurotrophic actions are expected to be promising alternatives. Small-molecule natural products, which have been used in dietary functional foods or in traditional medicine over the course of human history, have potential to be developed as new therapeutic agents against neurodegenerative conditions such as Alzheimer’s disease. In this book, the authors introduce a variety of natural products possessing neurotrophic properties such as neurogenesis, neurite outgrowth promotion (neuritogenesis), and neuroprotection and focus on the chemistry and biology of several neurotrophic natural products. |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical Term |
Natural products |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical Term |
Organic chemistry |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical Term |
Neurotrophic |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Fukuyama, Yoshiyasu |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Kubo, Miwa |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Harada, Kenichi |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Kinghorn, A. Douglas [ed.] |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Falk, Heinz [ed.] |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Gibbons, Simon [ed.] |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Asakawa, Yoshinori [ed.] |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Liu, Ji-Kai [ed.] |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Dirsch, Verena M. [ed.] |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
|---|
| Koha item type |
Books |
