000 -LEADER |
fixed length control field |
06755nam a2200685 i 4500 |
001 - CONTROL NUMBER |
control field |
6812982 |
003 - CONTROL NUMBER IDENTIFIER |
control field |
IEEE |
005 - DATE AND TIME OF LATEST TRANSACTION |
control field |
20200413152900.0 |
006 - FIXED-LENGTH DATA ELEMENTS--ADDITIONAL MATERIAL CHARACTERISTICS |
fixed length control field |
m eo d |
007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION |
fixed length control field |
cr cn |||m|||a |
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
fixed length control field |
110113s2011 caua foab 000 0 eng d |
020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
International Standard Book Number |
9781598299120 (electronic bk.) |
020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
Canceled/invalid ISBN |
9781598299113 (pbk.) |
024 7# - OTHER STANDARD IDENTIFIER |
Standard number or code |
10.2200/S00312ED1V01Y201011SBI002 |
Source of number or code |
doi |
035 ## - SYSTEM CONTROL NUMBER |
System control number |
(CaBNVSL)gtp00545630 |
035 ## - SYSTEM CONTROL NUMBER |
System control number |
(OCoLC)707877342 |
040 ## - CATALOGING SOURCE |
Original cataloging agency |
CaBNVSL |
Transcribing agency |
CaBNVSL |
Modifying agency |
CaBNVSL |
050 #4 - LIBRARY OF CONGRESS CALL NUMBER |
Classification number |
R857.B54 |
Item number |
M443 2011 |
060 #4 - NATIONAL LIBRARY OF MEDICINE CALL NUMBER |
Classification number |
QT 36 |
Item number |
M443b 2011 |
082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER |
Classification number |
610.28 |
Edition number |
22 |
100 1# - MAIN ENTRY--PERSONAL NAME |
Personal name |
Meer, Jan Roelof van der. |
245 10 - TITLE STATEMENT |
Title |
Bacterial sensors |
Medium |
[electronic resource] : |
Remainder of title |
synthetic design and application principles / |
Statement of responsibility, etc. |
Jan Roelof van der Meer. |
260 ## - PUBLICATION, DISTRIBUTION, ETC. |
Place of publication, distribution, etc. |
San Rafael, Calif. (1537 Fourth Street, San Rafael, CA 94901 USA) : |
Name of publisher, distributor, etc. |
Morgan & Claypool, |
Date of publication, distribution, etc. |
c2011. |
300 ## - PHYSICAL DESCRIPTION |
Extent |
1 electronic text (ix, 153 p.) : |
Other physical details |
ill., digital file. |
490 1# - SERIES STATEMENT |
Series statement |
Synthesis lectures on synthetic biology, |
International Standard Serial Number |
2151-0016 ; |
Volume/sequential designation |
# 2 |
538 ## - SYSTEM DETAILS NOTE |
System details note |
Mode of access: World Wide Web. |
538 ## - SYSTEM DETAILS NOTE |
System details note |
System requirements: Adobe Acrobat Reader. |
500 ## - GENERAL NOTE |
General note |
Part of: Synthesis digital library of engineering and computer science. |
500 ## - GENERAL NOTE |
General note |
Series from website. |
504 ## - BIBLIOGRAPHY, ETC. NOTE |
Bibliography, etc. note |
Includes bibliographical references. |
505 0# - FORMATTED CONTENTS NOTE |
Formatted contents note |
1. Short history of the use of bacteria for biosensing and bioreporting -- Early warning systems -- Early use of bacterial 'bioreporters' -- References -- |
505 0# - FORMATTED CONTENTS NOTE |
Formatted contents note |
2. Genetic engineering concepts -- Introduction to genetic sensing/-reporting circuits -- Central idea -- Intercept design -- Orthogonal design -- Design parts -- Use of transcriptional activators -- Choice of regulatory proteins -- The XylR/DmpR family of transcription activators -- The HbpR system -- Use of transcriptional repressors -- Regulators from heavy metal resistance -- The MerR system -- ArsR-based designs for arsenic detection -- Network interception designs -- General motivation -- SOS response network intercept design -- Promoter engineering -- General notions -- Promoter engineering in the Ars system -- Physiological control of the XylR-regulated Pu promoter -- Dual responsive control switches -- Directed evolution of promoters -- Response heterogeneity in populations -- Engineering new effector specificities -- General concept -- Effector domain mutagenesis in XylR/DmpR-type proteins -- Effector binding pocket modeling -- Aptamers -- Complex signal-transduction chains -- General concept -- Periplasmic binding proteins and phosphotransfer relay -- Multinode networks -- Logic gates, transcriptional noise, amplification -- Reporter proteins -- Choice and specificities of common reporter proteins -- Reporter gene vectors -- Embedding of sensing/-reporting circuits in a cellular chassis -- References -- |
505 0# - FORMATTED CONTENTS NOTE |
Formatted contents note |
3. Measuring with bioreporters -- Assay principles -- Relative and absolute measurements -- End-point and kinetic measurements, measurement transformations -- Population measurements -- Spiking -- Theory of analyte provision and transport -- Calculation of compound concentrations in reporter cells -- Non-diffusive and non-conservative bioreporters -- Concept of bioavailability and bioaccessibility -- Bioavailable fractions -- Bioavailability and bioaccessibility reporter measurements -- Bioreporter assay types -- Aqueous assays -- Gas phase measurements -- Solid phase assays -- Method detection limits, accuracy and precision -- References -- |
505 0# - FORMATTED CONTENTS NOTE |
Formatted contents note |
4. Epilogue -- Summary -- Future directions -- References -- |
505 0# - FORMATTED CONTENTS NOTE |
Formatted contents note |
A. Bacterial bioreporter designs targeting organic compounds -- References -- B. Bacterial bioreporter designs targeting (heavy) metals and metalloids -- References -- C. Bacterial bioreporter designs responsive to toxicity or stress conditions -- References -- D. Example bioreporter protocols -- Quantitative arsenite measurements with an E. coli LuxAB Luciferase bioreporter -- References -- Arsenic measurement using an E. coli GFP biosensor by epifluorescence microscopy -- References -- Arsenic measurements with an E. coli beta-galactoside bioreporter -- References -- Sample pretreatment -- Water -- Rice -- References -- Author's biography. |
506 1# - RESTRICTIONS ON ACCESS NOTE |
Terms governing access |
Abstract freely available; full-text restricted to subscribers or individual document purchasers. |
510 0# - CITATION/REFERENCES NOTE |
Name of source |
Compendex |
510 0# - CITATION/REFERENCES NOTE |
Name of source |
INSPEC |
510 0# - CITATION/REFERENCES NOTE |
Name of source |
Google scholar |
510 0# - CITATION/REFERENCES NOTE |
Name of source |
Google book search |
520 3# - SUMMARY, ETC. |
Summary, etc. |
Bacterial reporters are live, genetically engineered cells with promising application in bioanalytics. They contain genetic circuitry to produce a cellular sensing element, which detects the target compound and relays the detection to specific synthesis of so-called reporter proteins (the presence or activity of which is easy to quantify). Bioassays with bacterial reporters are a useful complement to chemical analytics because they measure biological responses rather than total chemical concentrations. Simple bacterial reporter assays may also replace more costly chemical methods as a first line sample analysis technique. Recent promising developments integrate bacterial reporter cells with microsystems to produce bacterial biosensors. This lecture presents an in-depth treatment of the synthetic biological design principles of bacterial reporters, the engineering of which started as simple recombinant DNA puzzles, but has now become a more rational approach of choosing and combining sensing, controlling and reporting DNA 'parts'. Several examples of existing bacterial reporter designs and their genetic circuitry will be illustrated. Besides the design principles, the lecture also focuses on the application principles of bacterial reporter assays.A variety of assay formats will be illustrated, and principles of quantification will be dealt with. In addition to this discussion, substantial reference material is supplied in various Annexes. |
530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE |
Additional physical form available note |
Also available in print. |
588 ## - SOURCE OF DESCRIPTION NOTE |
Source of description note |
Title from PDF t.p. (viewed on January 13, 2011). |
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Biosensors. |
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Genetic engineering. |
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Biological assay. |
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Reporter genes. |
650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Biosensing Techniques. |
650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Genetic Engineering. |
650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Biological Assay. |
650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Genes, Reporter. |
653 ## - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
Biosensor |
653 ## - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
Bioreporter |
653 ## - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
Synthetic biology |
653 ## - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
Promoter engineering |
776 08 - ADDITIONAL PHYSICAL FORM ENTRY |
Relationship information |
Print version: |
International Standard Book Number |
9781598299113 |
830 #0 - SERIES ADDED ENTRY--UNIFORM TITLE |
Uniform title |
Synthesis digital library of engineering and computer science. |
830 #0 - SERIES ADDED ENTRY--UNIFORM TITLE |
Uniform title |
Synthesis lectures on synthetic biology, |
International Standard Serial Number |
2151-0016 ; |
Volume/sequential designation |
# 2. |
856 42 - ELECTRONIC LOCATION AND ACCESS |
Materials specified |
Abstract with links to resource |
Uniform Resource Identifier |
http://ieeexplore.ieee.org/servlet/opac?bknumber=6812982 |