| 000 -LEADER |
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06677nam a22005055i 4500 |
| 001 - CONTROL NUMBER |
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| control field |
978-1-59745-293-9 |
| 003 - CONTROL NUMBER IDENTIFIER |
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| control field |
DE-He213 |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
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| control field |
20161121230840.0 |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION |
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cr nn 008mamaa |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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100301s2008 xxu| s |||| 0|eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
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| International Standard Book Number |
9781597452939 |
| -- |
978-1-59745-293-9 |
| 024 7# - OTHER STANDARD IDENTIFIER |
|---|
| Standard number or code |
10.1007/978-1-59745-293-9 |
| Source of number or code |
doi |
| 050 #4 - LIBRARY OF CONGRESS CALL NUMBER |
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| Classification number |
RC254-282 |
| 072 #7 - SUBJECT CATEGORY CODE |
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| Subject category code |
MJCL |
| Source |
bicssc |
| 072 #7 - SUBJECT CATEGORY CODE |
|---|
| Subject category code |
MED062000 |
| Source |
bisacsh |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER |
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| Classification number |
616.994 |
| Edition number |
23 |
| 245 10 - TITLE STATEMENT |
|---|
| Title |
Transforming Growth Factor-β in Cancer Therapy, Volume II |
| Medium |
[electronic resource] : |
| Remainder of title |
Cancer Treatment and Therapy / |
| Statement of responsibility, etc. |
edited by Sonia B. Jakowlew. |
| 264 #1 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE |
|---|
| Place of production, publication, distribution, manufacture |
Totowa, NJ : |
| Name of producer, publisher, distributor, manufacturer |
Humana Press, |
| Date of production, publication, distribution, manufacture, or copyright notice |
2008. |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Extent |
XXVI, 786 p. 164 illus., 4 illus. in color. |
| Other physical details |
online resource. |
| 336 ## - CONTENT TYPE |
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| Content type term |
text |
| Content type code |
txt |
| Source |
rdacontent |
| 337 ## - MEDIA TYPE |
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| Media type term |
computer |
| Media type code |
c |
| Source |
rdamedia |
| 338 ## - CARRIER TYPE |
|---|
| Carrier type term |
online resource |
| Carrier type code |
cr |
| Source |
rdacarrier |
| 347 ## - DIGITAL FILE CHARACTERISTICS |
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| File type |
text file |
| Encoding format |
PDF |
| Source |
rda |
| 490 1# - SERIES STATEMENT |
|---|
| Series statement |
Cancer Drug Discovery and Development |
| 505 0# - FORMATTED CONTENTS NOTE |
|---|
| Formatted contents note |
Transforming Growth Factor-? In Developing and Advanced Cancers -- Transforming Growth Factor-? Signaling in Pancreas Development and Pancreatic Disease -- Role of Transforming Growth Factor-? in the Pathogenesis of Human Head and Neck Squamous Cell Carcinoma -- TGF-?, Smads and Cervical Cancer -- TGF-? Signaling and Biglycan in Pancreatic Cancer -- TGF-? Signaling in Endometrial Cancer -- TGF-? Ligands, TGF-? Receptors, and Lung Cancer -- Role of TGF-? in Osteolytic Bone Metastases -- Hormonal Regulation of Transforming Growth Factor-? in Breast Cancer -- TGF-? and Progression of Esophageal Cancer -- TGF-? and HER2/ErbB2 and Breast Cancer Progression -- TGF-? Dependent T-Cell Regulation in Colitis and Colon Cancer -- Role of Transforming Growth Factor-? in the Kidney — Physiology and Pathology -- Perturbations of TGF-? Signaling in Leukocytes as Drivers of Leukemogenesis and Epithelial Tumorigenesis -- Transforming Growth Factor-? in Brain Functions and Dysfunctions -- Inhibition of TGF-? Signaling in Multiple Myeloma and Its Bone Marrow Microenvironment -- Key Roles of TGF-? and Smad3 in Prostate Cancer -- Smad Signaling in Leukemic Growth and Differentiation: Crosstalk Between Smad and Multiple Pathways Through Activation of the TGF-? Type I Receptor -- Transforming Growth Factor-? in Cancer Treatment and Therapy -- High-Throughput Screening of Protein Interaction Networks in the TGF? Interactome: Understanding the Signaling Mechanisms Driving Tumor Progression -- Tumor Suppressor and Pro-progression Roles for TGF-? in Breast Cancer -- Tumor Suppressors p53 and TGF? Converge to Regulate the Alpha-Fetoprotein Oncodevelopmental Tumor Marker -- TGF?: Roles in DNA Damage Responses -- The Rationale for and Effects of Targeting TGF-? for Glioma Therapy -- Tumor Suppressor Functions of TGF?1 in T Cells -- Therapeutic Effects of Adenovirus-Mediated Gene Transfer of TGF-? Signal Antagonists on Undesirable Epithelial-Mesenchymal Transition and Neovascularization -- Role of TGF-? in Tumor Protection and Antitumor Immunity -- Regulation of Angiogenesis and Tumor Growth by Thrombospondin-1 -- Cancer-Associated Fibroblasts and the Role of TGF-? -- Adoptive Transfer of Tumor Reactive TGF-? Insensitive CD8+ T-cells for Cancer Therapy -- DNA Methylation and Histone Deacetylation Inhibitors as Potential Therapeutic Agents for the Reconstitution of TGF-? Signaling in Breast Cancer -- Reactive Stroma and Evolution of Tumors: Integration of Transforming Growth Factor-?, Connective Tissue Growth Factor, and Fibroblast Growth Factor-2 Activities -- TGF-? Signaling and Vascular Morphogenesis -- Aberrant Transforming Growth Factor-? Signaling in Human Pancreatic Cancer: Translational Implications -- TGF-? and Stromal Influences Over Local Tumor Invasion -- TGF-? at the Crossroads Between Inflammation, Suppression and Cancer -- Development of Inhibitors of Transforming Growth Factor-? Signaling for Therapy -- Transforming Growth Factor-? (TGF-?) Signaling Inhibitors in Cancer Therapy -- Targeting TGF-? as a Strategy to Ameliorate Intestinal Side Effects of Radiation Therapy -- Targeting Transforming Growth Factor-? in Metastasis: In Vitro and In Vivo Mechanisms -- Targeted Downregulation of TGF-?2 with AP 12009 in Tumor Therapy -- Modulating TGF-? Receptor Signaling: A Novel Approach of Cancer Therapy -- Engineering TGF-? Traps: Artificially Dimerized Receptor Ectodomains as High-affinity Blockers of TGF-? Action -- The Use of Virtual Screening in ALK5 Kinase Inhibitor Discovery and Validation of Orally Active ALK5 Kinase Inhibitors in Oncology -- Soluble Type II Transforming Growth Factor-? Receptor Inhibits Tumorigenesis by Augmenting Host Antitumor Immunity -- Reversal of EMT by Small-Molecule Inhibitors of TGF-? Type I and II Receptors: Implications for Carcinoma Treatment -- Soluble TGF-? Type III Receptor Suppresses Malignant Progression of Human Cancer Cells -- Targeting Smad-Dependent TGF-? Signaling with Peptide Aptamers -- Rationale for Anti-TGF-? Antibody Therapy in Oncology. |
| 520 ## - SUMMARY, ETC. |
|---|
| Summary, etc. |
Transforming Growth Factor-ß in Cancer Therapy, Volumes 1 and 2, provides a compendium of findings about the role of transforming growth factor-ß (TGF-ß) in cancer treatment and therapy. The second volume, Cancer Treatment and Therapy, is divided into three parts. Part I examines transforming growth factor-ß in developing and advanced cancers. Part II details transforming growth factor-ß in cancer treatment and therapy. Part III includes an investigation into the development of inhibitors of transforming growth factor-ß signaling for therapy. This volume’s companion, Basic and Clinical Biology, examines transforming growth factor-ß signaling in normal physiology, cancer pathobiology, normal and tumor biology, and inflammation and fibrosis. Together, Transforming Growth Factor-ß in Cancer Therapy, Volumes 1 and 2, provide researchers and clinicians with a comprehensive and cutting-edge reference for the findings about the role of transforming growth factor-ß in biology and cancer treatment. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Medicine. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Cancer research. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Oncology. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Pathology. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Cell biology. |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Medicine & Public Health. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Oncology. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Cancer Research. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Cell Biology. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Pathology. |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Jakowlew, Sonia B. |
| Relator term |
editor. |
| 710 2# - ADDED ENTRY--CORPORATE NAME |
|---|
| Corporate name or jurisdiction name as entry element |
SpringerLink (Online service) |
| 773 0# - HOST ITEM ENTRY |
|---|
| Title |
Springer eBooks |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY |
|---|
| Relationship information |
Printed edition: |
| International Standard Book Number |
9781588297150 |
| 830 #0 - SERIES ADDED ENTRY--UNIFORM TITLE |
|---|
| Uniform title |
Cancer Drug Discovery and Development |
| 856 40 - ELECTRONIC LOCATION AND ACCESS |
|---|
| Uniform Resource Identifier |
http://dx.doi.org/10.1007/978-1-59745-293-9 |
| 912 ## - |
|---|
| -- |
ZDB-2-SME |
