| 000 -LEADER |
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| fixed length control field |
04485nam a22005055i 4500 |
| 001 - CONTROL NUMBER |
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| control field |
978-3-540-74806-9 |
| 003 - CONTROL NUMBER IDENTIFIER |
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| control field |
DE-He213 |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
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| control field |
20161121230809.0 |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION |
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| fixed length control field |
cr nn 008mamaa |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
100301s2008 gw | s |||| 0|eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
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| International Standard Book Number |
9783540748069 |
| -- |
978-3-540-74806-9 |
| 024 7# - OTHER STANDARD IDENTIFIER |
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| Standard number or code |
10.1007/978-3-540-74806-9 |
| Source of number or code |
doi |
| 050 #4 - LIBRARY OF CONGRESS CALL NUMBER |
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| Classification number |
RM1-950 |
| 072 #7 - SUBJECT CATEGORY CODE |
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| Subject category code |
MMG |
| Source |
bicssc |
| 072 #7 - SUBJECT CATEGORY CODE |
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| Subject category code |
MED071000 |
| Source |
bisacsh |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER |
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| Classification number |
615 |
| Edition number |
23 |
| 245 10 - TITLE STATEMENT |
|---|
| Title |
Modern Anesthetics |
| Medium |
[electronic resource] / |
| Statement of responsibility, etc. |
edited by Jürgen Schüttler, Helmut Schwilden. |
| 246 3# - VARYING FORM OF TITLE |
|---|
| Title proper/short title |
With contributions by numerous experts |
| 264 #1 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE |
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| Place of production, publication, distribution, manufacture |
Berlin, Heidelberg : |
| Name of producer, publisher, distributor, manufacturer |
Springer Berlin Heidelberg, |
| Date of production, publication, distribution, manufacture, or copyright notice |
2008. |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Extent |
XVI, 498 p. 112 illus., 5 illus. in color. |
| Other physical details |
online resource. |
| 336 ## - CONTENT TYPE |
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| Content type term |
text |
| Content type code |
txt |
| Source |
rdacontent |
| 337 ## - MEDIA TYPE |
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| Media type term |
computer |
| Media type code |
c |
| Source |
rdamedia |
| 338 ## - CARRIER TYPE |
|---|
| Carrier type term |
online resource |
| Carrier type code |
cr |
| Source |
rdacarrier |
| 347 ## - DIGITAL FILE CHARACTERISTICS |
|---|
| File type |
text file |
| Encoding format |
PDF |
| Source |
rda |
| 490 1# - SERIES STATEMENT |
|---|
| Series statement |
Handbook of Experimental Pharmacology, |
| International Standard Serial Number |
0171-2004 ; |
| Volume/sequential designation |
182 |
| 505 0# - FORMATTED CONTENTS NOTE |
|---|
| Formatted contents note |
Molecular Mechanisms of Anesthetic Action -- The Site of Anesthetic Action -- Inhibitory Ligand-Gated Ion Channels as Substrates for General Anesthetic Actions -- Actions of Anesthetics on Excitatory Transmitter-Gated Channels -- Voltage-Gated Ion Channels -- G-Protein-Coupled Receptors -- Modern Inhalation Anesthetics -- Inhalation Anaesthesia: From Diethyl Ether to Xenon -- General Anesthetics and Long-Term Neurotoxicity -- Special Aspects of Pharmacokinetics of Inhalation Anesthesia -- Inhalational Anaesthetics and Cardioprotection -- Non-Immobilizing Inhalational Anesthetic-Like Compounds -- Modern Intravenous Anesthetics -- Propofol -- Pharmacokinetics and Pharmacodynamics of GPI 15715 or Fospropofol (Aquavan Injection) — A Water-Soluble Propofol Prodrug -- Etomidate and Other Non-Barbiturates -- Remifentanil and Other Opioids -- Ketamine -- Midazolam and Other Benzodiazepines -- Pharmacokinetics-Pharmacodynamics Based Administration of Anesthetics -- The Effect of Altered Physiological States on Intravenous Anesthetics -- Anesthetics Drug Pharmacodynamics -- Defining Depth of Anesthesia -- Target Controlled Anaesthetic Drug Dosing -- Advanced Technologies and Devices for Inhalational Anesthetic Drug Dosing -- Hypnotic and Opioid Anesthetic Drug Interactions on the CNS, Focus on Response Surface Modeling. |
| 520 ## - SUMMARY, ETC. |
|---|
| Summary, etc. |
Some important constraints of anesthesia must be taken into consideration when the pharmacological properties of modern anesthetics are discussed. The most imp- tant of these could be that the target effect be achieved preferably within seconds, at most within a few minutes. Similarly, offset of drug action should be achieved within minutes rather hours. The target effects, such as unconsciousness, are pot- tially life-threatening, as are the side effects of modern anesthetics, such as respi- tory and cardiovascular depression. Finally, the patient’s purposeful responses are not available to guide drug dosage, because, either the patient is unconscious, or more problematically, the patient is aware but unable to communicate pain because of neuromuscular blockade. These constraints were already recognised 35 years ago, when in 1972 Volume XXX entitled “Modern Inhalation Anesthetics” appeared in this Handbook Series. The present volume is meant as a follow up and extension of that volume. At the beginning of the 1970’s anesthesia was commonly delivered by inhalation, with only very few exceptions. The clinical understanding of that time considered anesthesia as a unique state achieved by any of the inhalation anesthetics, in- pendent of their specific molecular structure. “The very mechanism of anesthetic action at the biophase” was discussed within the theoretical framework of the “u- tary theory of narcosis”. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Medicine. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Pharmacology. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Anesthesiology. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Emergency medicine. |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Biomedicine. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Pharmacology/Toxicology. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Anesthesiology. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Emergency Medicine. |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Schüttler, Jürgen. |
| Relator term |
editor. |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Schwilden, Helmut. |
| Relator term |
editor. |
| 710 2# - ADDED ENTRY--CORPORATE NAME |
|---|
| Corporate name or jurisdiction name as entry element |
SpringerLink (Online service) |
| 773 0# - HOST ITEM ENTRY |
|---|
| Title |
Springer eBooks |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY |
|---|
| Relationship information |
Printed edition: |
| International Standard Book Number |
9783540728139 |
| 830 #0 - SERIES ADDED ENTRY--UNIFORM TITLE |
|---|
| Uniform title |
Handbook of Experimental Pharmacology, |
| International Standard Serial Number |
0171-2004 ; |
| Volume/sequential designation |
182 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS |
|---|
| Uniform Resource Identifier |
http://dx.doi.org/10.1007/978-3-540-74806-9 |
| 912 ## - |
|---|
| -- |
ZDB-2-SBL |
