| 000 -LEADER |
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| fixed length control field |
03318nam a22005535i 4500 |
| 001 - CONTROL NUMBER |
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| control field |
978-3-540-73853-4 |
| 003 - CONTROL NUMBER IDENTIFIER |
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| control field |
DE-He213 |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
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| control field |
20161121230808.0 |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION |
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| fixed length control field |
cr nn 008mamaa |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
100301s2008 gw | s |||| 0|eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
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| International Standard Book Number |
9783540738534 |
| -- |
978-3-540-73853-4 |
| 024 7# - OTHER STANDARD IDENTIFIER |
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| Standard number or code |
10.1007/978-3-540-73853-4 |
| Source of number or code |
doi |
| 050 #4 - LIBRARY OF CONGRESS CALL NUMBER |
|---|
| Classification number |
RC109-216 |
| 072 #7 - SUBJECT CATEGORY CODE |
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| Subject category code |
MJCJ |
| Source |
bicssc |
| 072 #7 - SUBJECT CATEGORY CODE |
|---|
| Subject category code |
MED022090 |
| Source |
bisacsh |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER |
|---|
| Classification number |
616.9 |
| Edition number |
23 |
| 245 10 - TITLE STATEMENT |
|---|
| Title |
Control of Biofilm Infections by Signal Manipulation |
| Medium |
[electronic resource] / |
| Statement of responsibility, etc. |
edited by Naomi Balaban. |
| 264 #1 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE |
|---|
| Place of production, publication, distribution, manufacture |
Berlin, Heidelberg : |
| Name of producer, publisher, distributor, manufacturer |
Springer Berlin Heidelberg, |
| Date of production, publication, distribution, manufacture, or copyright notice |
2008. |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Extent |
XVI, 175 p. 56 illus., 13 illus. in color. |
| Other physical details |
online resource. |
| 336 ## - CONTENT TYPE |
|---|
| Content type term |
text |
| Content type code |
txt |
| Source |
rdacontent |
| 337 ## - MEDIA TYPE |
|---|
| Media type term |
computer |
| Media type code |
c |
| Source |
rdamedia |
| 338 ## - CARRIER TYPE |
|---|
| Carrier type term |
online resource |
| Carrier type code |
cr |
| Source |
rdacarrier |
| 347 ## - DIGITAL FILE CHARACTERISTICS |
|---|
| File type |
text file |
| Encoding format |
PDF |
| Source |
rda |
| 490 1# - SERIES STATEMENT |
|---|
| Series statement |
Springer Series on Biofilms, |
| International Standard Serial Number |
1863-9607 ; |
| Volume/sequential designation |
2 |
| 505 0# - FORMATTED CONTENTS NOTE |
|---|
| Formatted contents note |
Bacterial Cell-to-cell Communication (Quorum Sensing) -- Detection In Vitro of Quorum-Sensing Molecules and Their Inhibitors -- Quorum-Sensing Inhibitory Compounds -- Mathematical Modeling of Quorum-Sensing Control in Biofilms -- Animal Models Commonly Used to Study Quorum-Sensing Inhibitors -- In Vivo Studies: Inhibiting Biofilm-Associated Bacterial Infections Using QSIs -- Quorum Sensing in Streptococci -- Ironing Out the Biofilm Problem:The Role of Iron in Biofilm Formation -- Clinical Wound Healing Using Signal Inhibitors. |
| 520 ## - SUMMARY, ETC. |
|---|
| Summary, etc. |
The medical miracle of antibiotics is being eroded by the emergence and spread of bacterial drug resistance. This is compounded by the fact that bacterial biofilms are believed to be a common cause of persistent infections, when because growing in biofilms, bacteria are protected from the host’s immune response and from antibiotics. In addition, biofilms may spawn systemic infections by sloughing of planktonic bacteria, leading to dissemination, bacteremia, sepsis, and death. The number of patients affected by and dying from what can be considered as a "biofilm disease" is higher than heart disease and cancer combined, making medical biofilms the biggest single disease that the healthcare system is facing today. This book describes the molecular mechanisms of cell-to-cell communication among bacterial cells in a biofilm, the development of antibiofilm inhibitors, like quorum-sensing inhibitors, and the use of biofilm inhibitors to prevent and treat bacterial infections in humans and other animals. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Medicine. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Infectious diseases. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Proteomics. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Bioinformatics. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Cell biology. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Microbiology. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Bacteriology. |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Medicine & Public Health. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Infectious Diseases. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Microbiology. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Bacteriology. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Cell Biology. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Bioinformatics. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Proteomics. |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Balaban, Naomi. |
| Relator term |
editor. |
| 710 2# - ADDED ENTRY--CORPORATE NAME |
|---|
| Corporate name or jurisdiction name as entry element |
SpringerLink (Online service) |
| 773 0# - HOST ITEM ENTRY |
|---|
| Title |
Springer eBooks |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY |
|---|
| Relationship information |
Printed edition: |
| International Standard Book Number |
9783540738527 |
| 830 #0 - SERIES ADDED ENTRY--UNIFORM TITLE |
|---|
| Uniform title |
Springer Series on Biofilms, |
| International Standard Serial Number |
1863-9607 ; |
| Volume/sequential designation |
2 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS |
|---|
| Uniform Resource Identifier |
http://dx.doi.org/10.1007/978-3-540-73853-4 |
| 912 ## - |
|---|
| -- |
ZDB-2-SBL |
