| 000 -LEADER |
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| fixed length control field |
04291nam a22005535i 4500 |
| 001 - CONTROL NUMBER |
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| control field |
978-3-540-71021-9 |
| 003 - CONTROL NUMBER IDENTIFIER |
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| control field |
DE-He213 |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
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| control field |
20161121230807.0 |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION |
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| fixed length control field |
cr nn 008mamaa |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
140604s2007 gw | s |||| 0|eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
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| International Standard Book Number |
9783540710219 |
| -- |
978-3-540-71021-9 |
| 024 7# - OTHER STANDARD IDENTIFIER |
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| Standard number or code |
10.1007/978-3-540-71021-9 |
| Source of number or code |
doi |
| 050 #4 - LIBRARY OF CONGRESS CALL NUMBER |
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| Classification number |
QH573-671 |
| 072 #7 - SUBJECT CATEGORY CODE |
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| Subject category code |
PSF |
| Source |
bicssc |
| 072 #7 - SUBJECT CATEGORY CODE |
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| Subject category code |
SCI049000 |
| Source |
bisacsh |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER |
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| Classification number |
571.6 |
| Edition number |
23 |
| 245 10 - TITLE STATEMENT |
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| Title |
Molecular Genetics of Recombination |
| Medium |
[electronic resource] / |
| Statement of responsibility, etc. |
edited by Andr�s Aguilera, Rodney Rothstein. |
| 264 1# - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE |
|---|
| Place of production, publication, distribution, manufacture |
Berlin, Heidelberg : |
| Name of producer, publisher, distributor, manufacturer |
Springer Berlin Heidelberg : |
| -- |
Imprint: Springer, |
| Date of production, publication, distribution, manufacture, or copyright notice |
2007. |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Extent |
XXIV, 524 p. |
| Other physical details |
online resource. |
| 336 ## - CONTENT TYPE |
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| Content type term |
text |
| Content type code |
txt |
| Source |
rdacontent |
| 337 ## - MEDIA TYPE |
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| Media type term |
computer |
| Media type code |
c |
| Source |
rdamedia |
| 338 ## - CARRIER TYPE |
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| Carrier type term |
online resource |
| Carrier type code |
cr |
| Source |
rdacarrier |
| 347 ## - DIGITAL FILE CHARACTERISTICS |
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| File type |
text file |
| Encoding format |
PDF |
| Source |
rda1 |
| 490 ## - SERIES STATEMENT |
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| Series statement |
Topics in Current Genetics, |
| International Standard Serial Number |
1610-2096 ; |
| Volume/sequential designation |
170 |
| 505 ## - FORMATTED CONTENTS NOTE |
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| Formatted contents note |
Genetics of Recombination in the Model Bacterium Escherichia Coli -- Homologous Recombination in Low dC + dG Gram-Positive Bacteria -- The Bacterial RecA Protein: Structure, Function, and Regulation -- Biochemistry of Eukaryotic Homologous Recombination -- DNA helicases in recombination -- Holliday Junction Resolution -- Replication forks and replication checkpoints in repair -- Sister chromatid recombination -- Mating-Type Switching in S. Pombe -- Multiple Mechanisms of Repairing Meganuclease-Induced Double-Strand DNA Breaks in Budding Yeast -- The Cell Biology of Mitotic Recombination in Saccharomyces Cerevisiae -- The cell biology of homologous recombination -- BRCA2: safeguarding the genome through homologous recombination -- Meiotic recombination -- Site-specific recombination -- V(D)J Recombination: Mechanism and Consequences -- Nonhomologous End-Joining: Mechanisms, Conservation and Relationship to Illegitimate Recombination -- Analytical methods from the perspective of method standardization. |
| 520 ## - SUMMARY, ETC. |
|---|
| Summary, etc. |
Genetic recombination is an important process involved in shaping the genetic make up of progeny. Increasingly, it has become evident that recombination is a DNA repair pathway crucial during DNA replication in vegetatively growing cells. It plays a critical role in preserving the integrity of the genome by mediating the repair of DNA damage, which can occur during normal cellular metabolism as a result of oxidative stress, transcription, replication fork stalling or breakdown, or after the exposure to DNA damaging agents. Until recently, much of our knowledge on the mechanisms of genetic recombination has come from studies of prokaryotic and simple eukaryotic fungal systems. However, these studies have now been significantly extended to mammals, such that a comparative picture of the general factors and mechanisms of genetic recombination is beginning to emerge. Detailed genetic and biochemical studies have led to the isolation and characterization of many of the recombination-repair proteins in E. coli and S. cerevisiae, which in turn has led to the identification of homologues in human cells. The link between recombination defects and recombination proteins in a number of tumors as well as in human hereditary syndromes makes genetic recombination a cellular process of key importance not only in basic biology but also in biomedical studies. |
| 650 0# - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Life sciences. |
| 650 0# - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Biochemistry. |
| 650 0# - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Cell biology. |
| 650 0# - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Microbial genetics. |
| 650 0# - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Microbial genomics. |
| 650 0# - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Plant genetics. |
| 650 0# - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Animal genetics.1 |
| 650 4# - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Life Sciences.2 |
| 650 4# - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Cell Biology.2 |
| 650 4# - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Biochemistry, general.2 |
| 650 4# - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Microbial Genetics and Genomics.2 |
| 650 4# - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Plant Genetics & Genomics.2 |
| 650 4# - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Animal Genetics and Genomics.1 |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Aguilera, Andr�s. |
| Relator term |
editor.1 |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Rothstein, Rodney. |
| Relator term |
editor.2 |
| 710 ## - ADDED ENTRY--CORPORATE NAME |
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| Corporate name or jurisdiction name as entry element |
SpringerLink (Online service)0 |
| 773 ## - HOST ITEM ENTRY |
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| Title |
Springer eBooks08 |
| 776 ## - ADDITIONAL PHYSICAL FORM ENTRY |
|---|
| Relationship information |
Printed edition: |
| International Standard Book Number |
9783540710202 0 |
| 830 ## - SERIES ADDED ENTRY--UNIFORM TITLE |
|---|
| Uniform title |
Topics in Current Genetics, |
| International Standard Serial Number |
1610-2096 ; |
| Volume/sequential designation |
1740 |
| 856 ## - ELECTRONIC LOCATION AND ACCESS |
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| Uniform Resource Identifier |
http://dx.doi.org/10.1007/978-3-540-71021-9 |
| 912 ## - |
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| -- |
ZDB-2-SBL |
