000 -LEADER |
fixed length control field |
03328nam a22004815i 4500 |
001 - CONTROL NUMBER |
control field |
978-3-540-69161-7 |
003 - CONTROL NUMBER IDENTIFIER |
control field |
DE-He213 |
005 - DATE AND TIME OF LATEST TRANSACTION |
control field |
20161121230806.0 |
007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION |
fixed length control field |
cr nn 008mamaa |
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
fixed length control field |
100301s2007 gw | s |||| 0|eng d |
020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
International Standard Book Number |
9783540691617 |
-- |
978-3-540-69161-7 |
024 7# - OTHER STANDARD IDENTIFIER |
Standard number or code |
10.1007/978-3-540-69161-7 |
Source of number or code |
doi |
050 #4 - LIBRARY OF CONGRESS CALL NUMBER |
Classification number |
QH491 |
072 #7 - SUBJECT CATEGORY CODE |
Subject category code |
PSC |
Source |
bicssc |
072 #7 - SUBJECT CATEGORY CODE |
Subject category code |
SCI072000 |
Source |
bisacsh |
082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER |
Classification number |
571.8 |
Edition number |
23 |
245 10 - TITLE STATEMENT |
Title |
Asymmetric Cell Division |
Medium |
[electronic resource] / |
Statement of responsibility, etc. |
edited by Alvaro Macieira-Coelho. |
264 #1 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE |
Place of production, publication, distribution, manufacture |
Berlin, Heidelberg : |
Name of producer, publisher, distributor, manufacturer |
Springer Berlin Heidelberg, |
Date of production, publication, distribution, manufacture, or copyright notice |
2007. |
300 ## - PHYSICAL DESCRIPTION |
Extent |
XII, 248 p. |
Other physical details |
online resource. |
336 ## - CONTENT TYPE |
Content type term |
text |
Content type code |
txt |
Source |
rdacontent |
337 ## - MEDIA TYPE |
Media type term |
computer |
Media type code |
c |
Source |
rdamedia |
338 ## - CARRIER TYPE |
Carrier type term |
online resource |
Carrier type code |
cr |
Source |
rdacarrier |
347 ## - DIGITAL FILE CHARACTERISTICS |
File type |
text file |
Encoding format |
PDF |
Source |
rda |
490 1# - SERIES STATEMENT |
Series statement |
Progress in Molecular and Subcellular Biology, |
International Standard Serial Number |
0079-6484 ; |
Volume/sequential designation |
45 |
505 0# - FORMATTED CONTENTS NOTE |
Formatted contents note |
Asymmetric Cell Division in Plant Development -- Asymmetric Cell Division – How Flowering Plant Cells Get Their Unique Identity -- Symmetry Breaking in Stem Cells of the Basal Metazoan Hydra -- Asymmetric Cell Divisions in the Early Embryo of the Leech Helobdella robusta -- Asymmetric Divisions of Germline Cells -- Asymmetric Cell Division During Brain Morphogenesis -- Generating Asymmetry: With and Without Self-Renewal -- Cell Commitment by Asymmetric Division and Immune System Involvement -- Asymmetric Stem Cell Division in Development and Cancer -- Asymmetric Distribution of DNA Between Daughter Cells with Final Symmetry Breaking During Aging of Human Fibroblasts. |
520 ## - SUMMARY, ETC. |
Summary, etc. |
Cell biologists have recently become aware that the asymmetry of cell division is an important regulatory phenomenon in the fate of a cell. During development, cell diversity originates through asymmetry; in the adult organism asymmetric divisions regulate the stem cell reservoir and are a source of the drift that contributes to the aging of organisms with renewable cell compartments. Because of the concept of semi-conservative DNA synthesis, it was thought that the distribution of DNA between daughter cells was symmetric. The analysis of the phenomenon in cells during mitosis, however, revealed the asymmetry in the distribution of the genetic material that creates the drift contributing to aging of mammals. On the other hand, cancer cells can originate from a deregulation of asymmetry during mitosis in particular during stem cell expansion. The book describes the phenomenon in different organisms from plants to animals and addresses its implications for the development of the organism, cell differentiation, human aging and the biology of cancers. |
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Life sciences. |
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Cancer research. |
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Cell biology. |
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Developmental biology. |
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Life Sciences. |
650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Developmental Biology. |
650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Cell Biology. |
650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Cancer Research. |
700 1# - ADDED ENTRY--PERSONAL NAME |
Personal name |
Macieira-Coelho, Alvaro. |
Relator term |
editor. |
710 2# - ADDED ENTRY--CORPORATE NAME |
Corporate name or jurisdiction name as entry element |
SpringerLink (Online service) |
773 0# - HOST ITEM ENTRY |
Title |
Springer eBooks |
776 08 - ADDITIONAL PHYSICAL FORM ENTRY |
Relationship information |
Printed edition: |
International Standard Book Number |
9783540691600 |
830 #0 - SERIES ADDED ENTRY--UNIFORM TITLE |
Uniform title |
Progress in Molecular and Subcellular Biology, |
International Standard Serial Number |
0079-6484 ; |
Volume/sequential designation |
45 |
856 40 - ELECTRONIC LOCATION AND ACCESS |
Uniform Resource Identifier |
http://dx.doi.org/10.1007/978-3-540-69161-7 |
912 ## - |
-- |
ZDB-2-SBL |