| 000 -LEADER |
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04178nam a22004695i 4500 |
| 001 - CONTROL NUMBER |
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| control field |
978-1-4020-8399-0 |
| 003 - CONTROL NUMBER IDENTIFIER |
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| control field |
DE-He213 |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
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| control field |
20161121230801.0 |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION |
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| fixed length control field |
cr nn 008mamaa |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
100301s2008 ne | s |||| 0|eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
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| International Standard Book Number |
9781402083990 |
| -- |
978-1-4020-8399-0 |
| 024 7# - OTHER STANDARD IDENTIFIER |
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| Standard number or code |
10.1007/978-1-4020-8399-0 |
| Source of number or code |
doi |
| 050 #4 - LIBRARY OF CONGRESS CALL NUMBER |
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| Classification number |
RM1-950 |
| 072 #7 - SUBJECT CATEGORY CODE |
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| Subject category code |
MMG |
| Source |
bicssc |
| 072 #7 - SUBJECT CATEGORY CODE |
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| Subject category code |
MED071000 |
| Source |
bisacsh |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER |
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| Classification number |
615 |
| Edition number |
23 |
| 245 10 - TITLE STATEMENT |
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| Title |
Oxidants in Biology |
| Medium |
[electronic resource] : |
| Remainder of title |
A Question of Balance / |
| Statement of responsibility, etc. |
edited by Giuseppe Valacchi, Paul A. Davis. |
| 264 #1 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE |
|---|
| Place of production, publication, distribution, manufacture |
Dordrecht : |
| Name of producer, publisher, distributor, manufacturer |
Springer Netherlands, |
| Date of production, publication, distribution, manufacture, or copyright notice |
2008. |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Extent |
VIII, 328 p. |
| Other physical details |
online resource. |
| 336 ## - CONTENT TYPE |
|---|
| Content type term |
text |
| Content type code |
txt |
| Source |
rdacontent |
| 337 ## - MEDIA TYPE |
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| Media type term |
computer |
| Media type code |
c |
| Source |
rdamedia |
| 338 ## - CARRIER TYPE |
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| Carrier type term |
online resource |
| Carrier type code |
cr |
| Source |
rdacarrier |
| 347 ## - DIGITAL FILE CHARACTERISTICS |
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| File type |
text file |
| Encoding format |
PDF |
| Source |
rda |
| 505 0# - FORMATTED CONTENTS NOTE |
|---|
| Formatted contents note |
Old Players -- Hydrogen Peroxide: The Good, The Bad, and The Ugly -- Peroxynitrite: A Key Molecule in Skin Tissue Response to Different Types of Stress -- Cellular and Environmental Electrophiles: Balancing Redox Signaling, Inflammation, and Cell Death Pathways -- The Role of Reactive Nitrogen Species (RNS) in the Activation of Nuclear Factor Kappa B (NFkB) and Its Implications for Biological Systems: The Question of Balance -- Neutrophil-Derived Oxidants as Modulators of Polyunsaturated Fatty Acid Metabolism -- Fatty Acids in the Modulation of Reactive Oxygen Species Balance in Cancer -- The Question of Balance: The Interaction Between Blood and Ozone -- Iron and Erythrocytes: Physiological and Pathophysiological Aspects -- The Adventures of Superoxide Dismutase in Health and Disease: Superoxide in the Balance -- Glutathione Metabolism: Favorable Versus Unfavorable Effects -- Dual Roles of Oxidative Stress in the Lungs -- Antioxidants: How They Work -- New Players -- The Role of DUOX Isozymes in the Respiratory Tract Epithelium -- Hypertension, Diabetes, Oxidative Stress, and Cardiovascular Remodeling: Making the Connection with p66shc -- A Role of BRCA1-Associated Protein BARD1 in Oxidative Stress Response and Signaling and Proliferation Control -- Postprandial Events as a Trigger for Redox Unbalance: Role of Dietary Lipid Hydroperoxides and Antioxidants -- F2-Isoprostanes: Markers and Mediators of an Imbalanced Redox Status in the Liver. |
| 520 ## - SUMMARY, ETC. |
|---|
| Summary, etc. |
Oxidants, like other aspects of life, involves tradeoffs. Oxidants, whether intentionally produced or by-products of normal metabolism can either mediate a variety of critical biological processes but when present inappropriately cause extensive damage to biological molecules (DNA, proteins, and lipids). These effects can lead to either damage that is a major contributor to aging and degenerative diseases (or to other diseases such as cancer, cardiovascular disease, immune-system decline, brain dysfunction, and cataracts) or normal physiological function- tissue repair, defense against pathogens and cellular proliferation. On the other hand the body is equipped with a complex antioxidant/oxidant handling system which includes both enzymatic and nonenzymatic (i.e. small molecules such as flavonoids, ascorbate, tocopherol, and carotenoids) produced endogenously or derived from the diet. This book focuses on how the same molecules can have favorable or noxious effects depending on location, level and timing. Each chapter focuses on one particular molecule or oxidant/antioxidant system and provides a state of the art review of the current understanding regarding both positive and negative actions of the system under review. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Medicine. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Pharmacology. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Chemistry. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Cell biology. |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Biomedicine. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Pharmacology/Toxicology. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Chemistry/Food Science, general. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Cell Biology. |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Valacchi, Giuseppe. |
| Relator term |
editor. |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Davis, Paul A. |
| Relator term |
editor. |
| 710 2# - ADDED ENTRY--CORPORATE NAME |
|---|
| Corporate name or jurisdiction name as entry element |
SpringerLink (Online service) |
| 773 0# - HOST ITEM ENTRY |
|---|
| Title |
Springer eBooks |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY |
|---|
| Relationship information |
Printed edition: |
| International Standard Book Number |
9781402083983 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS |
|---|
| Uniform Resource Identifier |
http://dx.doi.org/10.1007/978-1-4020-8399-0 |
| 912 ## - |
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| -- |
ZDB-2-SBL |
