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Heat Shock Proteins and the Brain: Implications for Neurodegenerative Diseases and Neuroprotection (Record no. 503892)

000 -LEADER
fixed length control field 05462nam a22005655i 4500
001 - CONTROL NUMBER
control field 978-1-4020-8231-3
003 - CONTROL NUMBER IDENTIFIER
control field DE-He213
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20161121230800.0
007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION
fixed length control field cr nn 008mamaa
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 100301s2008 ne | s |||| 0|eng d
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 9781402082313
-- 978-1-4020-8231-3
024 7# - OTHER STANDARD IDENTIFIER
Standard number or code 10.1007/978-1-4020-8231-3
Source of number or code doi
050 #4 - LIBRARY OF CONGRESS CALL NUMBER
Classification number RC346-429.2
072 #7 - SUBJECT CATEGORY CODE
Subject category code MJN
Source bicssc
072 #7 - SUBJECT CATEGORY CODE
Subject category code MED056000
Source bisacsh
082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER
Classification number 616.8
Edition number 23
245 10 - TITLE STATEMENT
Title Heat Shock Proteins and the Brain: Implications for Neurodegenerative Diseases and Neuroprotection
Medium [electronic resource] /
Statement of responsibility, etc. edited by Alexzander A.A. Asea, Ian R. Brown.
264 #1 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE
Place of production, publication, distribution, manufacture Dordrecht :
Name of producer, publisher, distributor, manufacturer Springer Netherlands,
Date of production, publication, distribution, manufacture, or copyright notice 2008.
300 ## - PHYSICAL DESCRIPTION
Extent XVI, 373 p.
Other physical details online resource.
336 ## - CONTENT TYPE
Content type term text
Content type code txt
Source rdacontent
337 ## - MEDIA TYPE
Media type term computer
Media type code c
Source rdamedia
338 ## - CARRIER TYPE
Carrier type term online resource
Carrier type code cr
Source rdacarrier
347 ## - DIGITAL FILE CHARACTERISTICS
File type text file
Encoding format PDF
Source rda
490 1# - SERIES STATEMENT
Series statement Heat Shock Proteins ;
Volume/sequential designation 3
505 0# - FORMATTED CONTENTS NOTE
Formatted contents note Heat Shock Proteins and Neurodegenerative Diseases -- Chaperones and Polyglutamine Expansion Disorders -- Heat Shock Proteins, Unfolded Protein Response Chaperones and Alzheimer’s Disease -- Cellular and Molecular Mechanisms Underlying Parkinson’s Disease: The Role of Molecular Chaperones -- Heat Shock Proteins as Therapeutic Targets in Amyotrophic Lateral Sclerosis -- The Role of Chaperones and Co-Chaperones in Retinal Degenerative Diseases -- Neuroprotective Features Of Hsp90 Inhibitors Exhibiting Anti-Inflammatory Actions: Implications For Multiple Sclerosis -- Role of HspB1 and HspB8 in Hereditary Peripheral Neuropathies: Beyond the Chaperone Function -- Heat Shock Proteins and Neuroprotection -- Heat Shock Proteins Hsp70 and Hsp27 and Neural Cellular Protection -- Molecular Chaperones and Protection in Animal and Cellular Models of Ischemic Stroke -- Strategies for Conferring Neuroprotection and Countering the High Threshold for Induction of the Stress Response in Motor Neurons -- Use of Viral Gene Delivery Systems to Investigate the Neuroprotective Roles of Hsp70 and Hsp40 Proteins -- Heat Shock Proteins at the Synapse: Implications for Functional Protection of the Nervous System -- Extracellular Heat Shock Proteins and The Nervous System -- Release of Heat Shock Proteins and their Effects When in the Extracellular Space in the Nervous System -- Silencing of Metastasis-associated Gene 1 (Mta1) Stimulates Hsp70 Cellular Release and Neurite extension in Neuroblastoma Cells -- Extracellular Chaperones and Amyloids -- Aging, Control Of Life Span and Expression Of Heat Shock Proteins -- Neural Expression Of Small Heat Shock Proteins Influences Longevity And Resistance To Oxidative Stress -- Mechanistic Links Between Aging and Aggregation-Mediated Proteotoxicity: Role of HSF-1 and DAF-16 -- Protein Quality Control and Heat Shock Gene Expression in the Nervous System -- Serum Hsp70 Level as a Biomarker of Exceptional Longevity -- Heat Shock Proteins and the Brain: Implications for Neurodegenerative Diseases and Neuroprotection.
520 ## - SUMMARY, ETC.
Summary, etc. With the prevalence of neurodegenerative diseases on the rise as average life expectancy increases, the hunt for effective treatments and preventive measures for these disorders is a pressing challenge. Neurodegenerative disorders such as Alzheimer’s disease, Huntington’s disease, Parkinson’s disease and amyotrophic lateral sclerosis have been termed ‘protein misfolding disorders’ that are char- terized by the neural accumulation of protein aggregates. Manipulation of the cellular stress response involving the induction of heat shock proteins offers a the- peutic strategy to counter conformational changes in neural proteins that trigger pathogenic cascades resulting in neurodegenerative diseases. Heat shock proteins are protein repair agents that provide a line of defense against misfolded, aggregati- prone proteins. Heat Shock Proteins and the Brain: Implications for Neurodegenerative Diseases and Neuroprotection reviews current progress on neural heat shock proteins (HSP) in relation to neurodegenerative diseases (Part I), neuroprotection (Part II), ext- cellular HSP (Part III) and aging and control of life span (Part IV). Key basic and clinical research laboratories from major universities and hospitals around the world contribute chapters that review present research activity and importantly project the field into the future. The book is a must read for researchers, postdoctoral fellows and graduate students in the fields of Neuroscience, Neurodegenerative Diseases, Molecular Medicine, Aging, Physiology, Pharmacology and Pathology.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Medicine.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Human physiology.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Laboratory medicine.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Molecular biology.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Neurosciences.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Pharmacology.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Neurology.
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Medicine & Public Health.
650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Neurology.
650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Neurosciences.
650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Molecular Medicine.
650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Laboratory Medicine.
650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Human Physiology.
650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Pharmacology/Toxicology.
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Asea, Alexzander A.A.
Relator term editor.
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Brown, Ian R.
Relator term editor.
710 2# - ADDED ENTRY--CORPORATE NAME
Corporate name or jurisdiction name as entry element SpringerLink (Online service)
773 0# - HOST ITEM ENTRY
Title Springer eBooks
776 08 - ADDITIONAL PHYSICAL FORM ENTRY
Relationship information Printed edition:
International Standard Book Number 9781402082306
830 #0 - SERIES ADDED ENTRY--UNIFORM TITLE
Uniform title Heat Shock Proteins ;
Volume/sequential designation 3
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier http://dx.doi.org/10.1007/978-1-4020-8231-3
912 ## -
-- ZDB-2-SBL
Holdings
Withdrawn status Lost status Damaged status Not for loan Permanent Location Current Location Date acquired Barcode Date last seen Price effective from Koha item type
        PK Kelkar Library, IIT Kanpur PK Kelkar Library, IIT Kanpur 2016-11-21 EBK4179 2016-11-21 2016-11-21 E books

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