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05338nam a22004575i 4500 |
| 001 - CONTROL NUMBER |
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| control field |
978-0-387-77909-6 |
| 003 - CONTROL NUMBER IDENTIFIER |
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DE-He213 |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
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20161121230752.0 |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION |
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cr nn 008mamaa |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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100301s2008 xxu| s |||| 0|eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
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| International Standard Book Number |
9780387779096 |
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978-0-387-77909-6 |
| 024 7# - OTHER STANDARD IDENTIFIER |
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| Standard number or code |
10.1007/978-0-387-77909-6 |
| Source of number or code |
doi |
| 050 #4 - LIBRARY OF CONGRESS CALL NUMBER |
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| Classification number |
QR180-189.5 |
| 072 #7 - SUBJECT CATEGORY CODE |
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| Subject category code |
MJCM |
| Source |
bicssc |
| 072 #7 - SUBJECT CATEGORY CODE |
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| Subject category code |
MED044000 |
| Source |
bisacsh |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER |
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| Classification number |
616.079 |
| Edition number |
23 |
| 245 10 - TITLE STATEMENT |
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| Title |
Regulatory T Cells and Clinical Application |
| Medium |
[electronic resource] / |
| Statement of responsibility, etc. |
edited by Shuiping Jiang. |
| 264 #1 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE |
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| Place of production, publication, distribution, manufacture |
New York, NY : |
| Name of producer, publisher, distributor, manufacturer |
Springer US, |
| Date of production, publication, distribution, manufacture, or copyright notice |
2008. |
| 300 ## - PHYSICAL DESCRIPTION |
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| Extent |
XVIII, 590 p. 71 illus., 32 illus. in color. |
| Other physical details |
online resource. |
| 336 ## - CONTENT TYPE |
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| Content type term |
text |
| Content type code |
txt |
| Source |
rdacontent |
| 337 ## - MEDIA TYPE |
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| Media type term |
computer |
| Media type code |
c |
| Source |
rdamedia |
| 338 ## - CARRIER TYPE |
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| Carrier type term |
online resource |
| Carrier type code |
cr |
| Source |
rdacarrier |
| 347 ## - DIGITAL FILE CHARACTERISTICS |
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| File type |
text file |
| Encoding format |
PDF |
| Source |
rda |
| 505 0# - FORMATTED CONTENTS NOTE |
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| Formatted contents note |
Immunobiology of Regulatory T Cells -- Regulatory T Cells and the Control of Auto-Immunity: From day 3 Thymectomy to FoxP3+ Regulatory T Cells -- FoxP3 and Regulatory T Cells -- Thymic and Peripheral Generation of CD4 + Foxp3 + Regulatory T Cells -- The Role of IL-2 in the Development and Peripheral Homeostasis of Naturally Occurring CD4 + CD25 + Foxp3 + Regulatory T Cells -- IL-2 Signaling and CD4+ CD25+ Regulatory T Cells -- TGF-Beta and Regulatory T Cells -- TGF-? Regulates Reciprocal Differentiation of CD4 + CD25 + Foxp3 + Regulatory T Cells and IL-17-Producing Th17 Cells from Naïve CD4 + CD25 – T Cells -- Molecular Signalling in T Regulatory Cells -- Regulatory T Cells in Disease and Clinical Application -- CD4+Foxp3+Regulatory T Cells in Immune Tolerance -- Regulatory T Cell Control of Autoimmune Diabetes and Their Potential Therapeutic Application -- CD4+CD25+ Regulatory T Cells as Adoptive Cell Therapy for Autoimmune Disease and for the Treatment of Graft-Versus-Host Disease -- Natural CD4 + CD25 + Regulatory T Cells in Regulation of Autoimmune Disease -- Multiple Sclerosis and Regulatory T Cells -- CD4+CD25+ Regulatory T Cells and TGF-Beta in Mucosal Inflammation -- Induction of Adaptive CD4+CD25+Foxp3+ Regulatory T Cell Response in Autoimmune Disease -- Regulatory T Cells in Transplantation -- Regulatory T-cells in Therapeutic Transplantation Tolerance -- CD4 + CD25 + Regulatory T Cell Therapy for the Induction of Clinical Transplantation Tolerance -- Regulatory T Cells in Allergic Disease -- Regulatory T Cells and Tumour Immunotherapy -- Regulatory T Cells in Hepatitis and Hepatocellular Carcinoma -- CD4+CD25+ Regulatory T Cells in Viral Infections -- IL-10 and TGF-?-Producing Regulatory T Cells in Infection -- Human Type 1 T Regulatory Cells -- CD8+ T Regulatory Cells in Eye Derive Tolerance -- Immune Suppression by a Novel Population of CD8??+TCR??+ Regulatory T cells -- Innate Regulatory iNKT Cells -- Natural Killer T Cells Regulate the Development of Asthma -- The Development, Activation, Function and Mechanisms of Immunosuppressive Double Negative (DN) T Cells -- ?? T Cells in Immunoregulation. |
| 520 ## - SUMMARY, ETC. |
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| Summary, etc. |
A major process of rediscovery has taken place in the field of Cellular Immunology over the past 12 years—subsets of T lymphocytes exist that are specifically dedicated to regulation or as it should be more appropriately termed suppression of all aspects of immune responses. It was only after Prof. Sakaguchi identified the CD25 antigen in 1995 as a marker for a major population of T cells that had suppressor functions both in vitro and in vivo that the resurgence in the regulatory T cell area could begin. The regulatory T cells field has grown dramatically over the past decade. It is now impossible to read a journal that does not contain numerous papers whose titles deal with regulatory T cells. More importantly, it is also difficult to submit a new research grant proposal in any area of immunologic research that does not include a section on analysis on the contribution of regulatory T cells to the subject matter under study. Regulatory T cells can be best thought of today as "teenagers" ready to take on all the challenges of complex immune responses. In ten years, the field will certainly be more mature, and manipulation of regulatory T cell function by cellular biotherapy, antibodies and small molecules will be routine function of the clinical immunologist. - From Preface by Prof. Ethan Shevach, National Institute of Health, USA It has been for long debated whether suppressor/regulatory T cells did actually even exist. Today, this question is no longer accurate and the subject of regulatory T cells is the object of a constantly growing interest in immunologists and clinicians. There is no doubt that the history of Tregs will make a new big leap ahead. - From Chapter One by Prof. Shimon Sakaguchi, Kyoto University, Japan. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Medicine. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Immunology. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Medical microbiology. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Cell biology. |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Biomedicine. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Immunology. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Medical Microbiology. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Cell Biology. |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Jiang, Shuiping. |
| Relator term |
editor. |
| 710 2# - ADDED ENTRY--CORPORATE NAME |
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| Corporate name or jurisdiction name as entry element |
SpringerLink (Online service) |
| 773 0# - HOST ITEM ENTRY |
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| Title |
Springer eBooks |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY |
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| Relationship information |
Printed edition: |
| International Standard Book Number |
9780387779089 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS |
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| Uniform Resource Identifier |
http://dx.doi.org/10.1007/978-0-387-77909-6 |
| 912 ## - |
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ZDB-2-SBL |
