000 -LEADER |
fixed length control field |
03697nam a22004095i 4500 |
001 - CONTROL NUMBER |
control field |
978-0-387-76761-1 |
003 - CONTROL NUMBER IDENTIFIER |
control field |
DE-He213 |
005 - DATE AND TIME OF LATEST TRANSACTION |
control field |
20161121230752.0 |
007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION |
fixed length control field |
cr nn 008mamaa |
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
fixed length control field |
100715s2008 xxu| s |||| 0|eng d |
020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
International Standard Book Number |
9780387767611 |
-- |
978-0-387-76761-1 |
024 7# - OTHER STANDARD IDENTIFIER |
Standard number or code |
10.1007/978-0-387-76761-1 |
Source of number or code |
doi |
050 #4 - LIBRARY OF CONGRESS CALL NUMBER |
Classification number |
RC321-580 |
072 #7 - SUBJECT CATEGORY CODE |
Subject category code |
PSAN |
Source |
bicssc |
072 #7 - SUBJECT CATEGORY CODE |
Subject category code |
MED057000 |
Source |
bisacsh |
082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER |
Classification number |
612.8 |
Edition number |
23 |
245 10 - TITLE STATEMENT |
Title |
Reelin Glycoprotein |
Medium |
[electronic resource] : |
Remainder of title |
Structure, Biology and Roles in Health and Disease / |
Statement of responsibility, etc. |
edited by S. Hossein Fatemi. |
264 #1 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE |
Place of production, publication, distribution, manufacture |
New York, NY : |
Name of producer, publisher, distributor, manufacturer |
Springer New York, |
Date of production, publication, distribution, manufacture, or copyright notice |
2008. |
300 ## - PHYSICAL DESCRIPTION |
Extent |
XXIII, 443 p. |
Other physical details |
online resource. |
336 ## - CONTENT TYPE |
Content type term |
text |
Content type code |
txt |
Source |
rdacontent |
337 ## - MEDIA TYPE |
Media type term |
computer |
Media type code |
c |
Source |
rdamedia |
338 ## - CARRIER TYPE |
Carrier type term |
online resource |
Carrier type code |
cr |
Source |
rdacarrier |
347 ## - DIGITAL FILE CHARACTERISTICS |
File type |
text file |
Encoding format |
PDF |
Source |
rda |
505 0# - FORMATTED CONTENTS NOTE |
Formatted contents note |
The Reelin Gene and Its Functions in Brain Development -- Apolipoprotein E Receptor 2 and Very-Low-Density Lipoprotein Receptor: An Overview -- Chemistry of Reelin -- The C-Terminal Region of Reelin: Structure and Function -- Crystal Structure of Reelin Repeats -- Comparative Anatomy and Evolutionary Roles of Reelin -- Reelin/Dab1 Signaling in the Developing Cerebral Cortex -- Ultrastructural Localization of Reelin -- Reelin and Cyclin-Dependent Kinase 5 -- Reelin and the Cerebellum -- Reelin and Radial Glial Cells -- Reelin and Cognition -- Protein Kinases and Signaling Pathways that Are Activated by Reelin -- The Relationship of Oxytocin and Reelin in the Brain -- Reelin and Thyroid Hormone -- A Tale of Two Genes: Reelin and BDNF -- Reelin, Liver, and Lymphatics -- Reelin and Cajal-Retzius Cells -- Reelin and Odontogenesis -- Homozygous and Heterozygous Reeler Mouse Mutants -- Reelin and Lissencephaly -- The Role of Reelin in Etiology and Treatment of Psychiatric Disorders -- Reelin Downregulation as a Prospective Treatment Target for GABAergic Dysfunction in Schizophrenia -- Epigenetic Modulation of Reelin Function in Schizophrenia and Bipolar Disorder -- Reelin Gene Polymorphisms in Autistic Disorder -- Alzheimer’s Disease and Reelin -- Reelin and Stroke -- Reelin and Pancreatic Cancer. |
520 ## - SUMMARY, ETC. |
Summary, etc. |
Reelin glycoprotein is a major secretory protein with important roles in embryogenesis and during adult life. Reelin gene mutations or deficiency of the protein product cause abnormal cortical development and reelin signaling impairment in brain. Since the first discovery of the reelin mutant mouse in 1951 by Falconer, and later discovery of the gene for reelin in 1995, there has been an explosion of new knowledge about this important molecule. Reelin Glycoprotein: Structure, Biology and Roles in Health and Disease, written by an international panel of experts, summarizes the state of the knowledge on various aspects of reelin. Topics include the reelin gene and its receptors, downstream effector molecules in reelin signaling cascade, chemistry and structure of reelin, comparative anatomy of reelin, presence of reelin in various body tissues, reelin mutations, and abnormalities of reelin production in neuropsychiatric disorders and cancer. This book will serve as a foundation for analysis of this emerging novel protein for all neuroscientists and clinicians. |
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Medicine. |
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Neurosciences. |
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Biomedicine. |
650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Neurosciences. |
700 1# - ADDED ENTRY--PERSONAL NAME |
Personal name |
Fatemi, S. Hossein. |
Relator term |
editor. |
710 2# - ADDED ENTRY--CORPORATE NAME |
Corporate name or jurisdiction name as entry element |
SpringerLink (Online service) |
773 0# - HOST ITEM ENTRY |
Title |
Springer eBooks |
776 08 - ADDITIONAL PHYSICAL FORM ENTRY |
Relationship information |
Printed edition: |
International Standard Book Number |
9780387767604 |
856 40 - ELECTRONIC LOCATION AND ACCESS |
Uniform Resource Identifier |
http://dx.doi.org/10.1007/978-0-387-76761-1 |
912 ## - |
-- |
ZDB-2-SBL |