| 000 -LEADER |
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| fixed length control field |
03542nam a22005295i 4500 |
| 001 - CONTROL NUMBER |
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| control field |
978-0-387-72232-0 |
| 003 - CONTROL NUMBER IDENTIFIER |
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| control field |
DE-He213 |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
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| control field |
20161121230750.0 |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION |
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| fixed length control field |
cr nn 008mamaa |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
100602s2007 xxu| s |||| 0|eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
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| International Standard Book Number |
9780387722320 |
| -- |
978-0-387-72232-0 |
| 024 7# - OTHER STANDARD IDENTIFIER |
|---|
| Standard number or code |
10.1007/978-0-387-72232-0 |
| Source of number or code |
doi |
| 050 #4 - LIBRARY OF CONGRESS CALL NUMBER |
|---|
| Classification number |
QR180-189.5 |
| 072 #7 - SUBJECT CATEGORY CODE |
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| Subject category code |
MJCM |
| Source |
bicssc |
| 072 #7 - SUBJECT CATEGORY CODE |
|---|
| Subject category code |
MED044000 |
| Source |
bisacsh |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER |
|---|
| Classification number |
616.079 |
| Edition number |
23 |
| 245 10 - TITLE STATEMENT |
|---|
| Title |
Mucosal Immune Defense: Immunoglobulin A |
| Medium |
[electronic resource] / |
| Statement of responsibility, etc. |
edited by Charlotte Slayton Kaetzel. |
| 264 #1 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE |
|---|
| Place of production, publication, distribution, manufacture |
Boston, MA : |
| Name of producer, publisher, distributor, manufacturer |
Springer US, |
| Date of production, publication, distribution, manufacture, or copyright notice |
2007. |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Extent |
XVI, 434 p. |
| Other physical details |
online resource. |
| 336 ## - CONTENT TYPE |
|---|
| Content type term |
text |
| Content type code |
txt |
| Source |
rdacontent |
| 337 ## - MEDIA TYPE |
|---|
| Media type term |
computer |
| Media type code |
c |
| Source |
rdamedia |
| 338 ## - CARRIER TYPE |
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| Carrier type term |
online resource |
| Carrier type code |
cr |
| Source |
rdacarrier |
| 347 ## - DIGITAL FILE CHARACTERISTICS |
|---|
| File type |
text file |
| Encoding format |
PDF |
| Source |
rda |
| 505 0# - FORMATTED CONTENTS NOTE |
|---|
| Formatted contents note |
The Structure of IgA -- IgA Plasma Cell Development -- Epithelial Transport of IgA by the Polymeric Immunoglobulin Receptor -- Fc Receptors for IgA -- Regulation of the Mucosal IgA System -- Biological Functions of IgA -- Protection of Mucosal Epithelia by IgA: Intracellular Neutralization and Excretion of Antigens -- Novel Functions for Mucosal SIgA -- IgA and Antigen Sampling -- IgA and Intestinal Homeostasis -- IgA and Respiratory Immunity -- IgA and Reproductive Tract Immunity -- IgA-Associated Diseases -- Mucosal SIgA Enhancement: Development of Safe and Effective Mucosal Adjuvants and Mucosal Antigen Delivery Vehicles -- Recombinant IgA Antibodies. |
| 520 ## - SUMMARY, ETC. |
|---|
| Summary, etc. |
Antibodies of the IgA class form the front line of immune defense at mucosal surfaces lining the gastrointestinal, respiratory and genital tracts. These IgA antibodies promote peaceful co-existence with beneficial microorganisms, such as gut bacteria that assist in digestion and nutrient production, while selectively neutralizing pathogenic microorganisms and harmful environmental substances. This book, authored by international experts in the field of IgA immunology, presents a comprehensive and timely overview of current knowledge of IgA structure and function. Topics include the basic science of IgA biochemistry and molecular biology, general and tissue-specific aspects of IgA function, and the clinical relevance of IgA in infection, autoimmunity, immunodeficiency and cancer. The final chapters describe state-of-the art applications of molecular genetics for the production of vaccines and therapeutics targeting IgA. The unique focus on IgA, the most abundant molecule in the mucosal immune system, differentiates this book from more general texts in the area of mucosal immunology. This book should be useful for researchers, educators, clinicians and students interested in a concise source of up-to-date information on the central role of IgA in mucosal immune defense. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Medicine. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Immunology. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Pharmacology. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Virology. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Allergy. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Infectious diseases. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Microbiology. |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Biomedicine. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Immunology. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Microbiology. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Infectious Diseases. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Virology. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Pharmacology/Toxicology. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Allergology. |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Kaetzel, Charlotte Slayton. |
| Relator term |
editor. |
| 710 2# - ADDED ENTRY--CORPORATE NAME |
|---|
| Corporate name or jurisdiction name as entry element |
SpringerLink (Online service) |
| 773 0# - HOST ITEM ENTRY |
|---|
| Title |
Springer eBooks |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY |
|---|
| Relationship information |
Printed edition: |
| International Standard Book Number |
9780387722313 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS |
|---|
| Uniform Resource Identifier |
http://dx.doi.org/10.1007/978-0-387-72232-0 |
| 912 ## - |
|---|
| -- |
ZDB-2-SBL |
