| 000 -LEADER |
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| fixed length control field |
04311nam a22005415i 4500 |
| 001 - CONTROL NUMBER |
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| control field |
978-4-431-27879-5 |
| 003 - CONTROL NUMBER IDENTIFIER |
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| control field |
DE-He213 |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
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| control field |
20161121230710.0 |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION |
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| fixed length control field |
cr nn 008mamaa |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
100301s2005 ja | s |||| 0|eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
|---|
| International Standard Book Number |
9784431278795 |
| -- |
978-4-431-27879-5 |
| 024 7# - OTHER STANDARD IDENTIFIER |
|---|
| Standard number or code |
10.1007/4-431-27879-6 |
| Source of number or code |
doi |
| 050 #4 - LIBRARY OF CONGRESS CALL NUMBER |
|---|
| Classification number |
QH573-671 |
| 072 #7 - SUBJECT CATEGORY CODE |
|---|
| Subject category code |
PSF |
| Source |
bicssc |
| 072 #7 - SUBJECT CATEGORY CODE |
|---|
| Subject category code |
SCI049000 |
| Source |
bisacsh |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER |
|---|
| Classification number |
571.6 |
| Edition number |
23 |
| 245 10 - TITLE STATEMENT |
|---|
| Title |
Non-viral Gene Therapy |
| Medium |
[electronic resource] : |
| Remainder of title |
Gene Design and Delivery / |
| Statement of responsibility, etc. |
edited by Kazunari Taira, Kazunori Kataoka, Takuro Niidome. |
| 264 #1 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE |
|---|
| Place of production, publication, distribution, manufacture |
Tokyo : |
| Name of producer, publisher, distributor, manufacturer |
Springer Tokyo, |
| Date of production, publication, distribution, manufacture, or copyright notice |
2005. |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Extent |
XII, 487 p. |
| Other physical details |
online resource. |
| 336 ## - CONTENT TYPE |
|---|
| Content type term |
text |
| Content type code |
txt |
| Source |
rdacontent |
| 337 ## - MEDIA TYPE |
|---|
| Media type term |
computer |
| Media type code |
c |
| Source |
rdamedia |
| 338 ## - CARRIER TYPE |
|---|
| Carrier type term |
online resource |
| Carrier type code |
cr |
| Source |
rdacarrier |
| 347 ## - DIGITAL FILE CHARACTERISTICS |
|---|
| File type |
text file |
| Encoding format |
PDF |
| Source |
rda |
| 505 0# - FORMATTED CONTENTS NOTE |
|---|
| Formatted contents note |
Molecules for Gene Therapy -- Recent Progress in Non-viral Gene Delivery -- Physical Chemistry of DNA-Carrier Complexes -- Liposomes -- Polymeric Gene Carriers -- Development of a Supramolecular Nanocarrier for Gene Delivery Based on Cationic Block Copolymers -- Chitosan -- Dendrimers as DNA Carriers -- Use of Synthetic Peptides for Non-viral Gene Delivery -- An Oligonucleotide Carrier Based on ?-1,3-Glucans -- Biological and Chemical Hybrid Vectors -- Controlled Gene Delivery -- Pharmacokinetics of Gene Delivery in Cells -- Active DNA Release from Complexes -- Controlled Release of DNA Using Thermoresponsive Polymers -- Active Transport of Exogenous Genes into the Nucleus -- Controlled Intracellular Localization of Oligonucleotides by Chemical Conjugation -- Functional Nucleotide Sequences Capable of Promoting Non-viral Genetic Transfer -- Shielding of Cationic Charge of the DNA Complex to Avoid Nonspecific Interactions for In Vivo Gene Delivery -- In Vivo Gene Transfer by Ligand-Modified Gene Carriers -- Optimizing Polyplexes into Synthetic Viruses for Tumor-Targeted Gene Therapy -- Gene Transfer and Target Diseases -- Clinical Trials Using Non-viral Gene Delivery Systems -- Current Protocols of Gene Delivery -- Evaluation of Size and Zeta Potential of DNA/Carrier Complexes -- Observation of DNA/Carrier Complexes Under Fluorescence Microscopy -- Synthesis of Chemically Modified Chitosan and a Study of Its Gene Transfection Efficiency -- Newly Designed DNA Fragments for Gene Correction -- Evaluation of Gene Expression In Vivo After Intravenous and Intraportal Administration of Lipoplexes -- Evaluation by Southern Blot Hybridization of DNA Administered with a Gene Carrier to Organs -- Evaluation of the Immune Response After Administration of Plasmid DNA-Non-viral Vector Complexes -- Gateway RNAi -- Design of Genes Based on Current RNA Technology -- Design of Intracellularly Active Ribozymes and siRNAs -- RNAi-Based Inhibition Specific for Mutant Alleles in Autosomal Dominant Diseases: Sequence-Dependent and -Independent Discrimination of Mutant and Wild-Type Alleles by siRNA -- In Vivo RNA Interference: Another Tool in the Box? -- Suppression of Gene Expression via Chromatin Remodeling and the siRNA-Induced Silencing of Transcription -- Intracellular Delivery of Nucleic Acids: Differences Between Transfection and siFection Reflect Differences Between DNA and RNA, and Between Oligodeoxynucleotides and Oligonucleotides -- In Vivo Antitumor Activity of a New Cationic Liposome siRNA Complex -- Enhancing RNAi with Synthetic RNA Duplexes. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Life sciences. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Molecular biology. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Biotechnology. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Biochemical engineering. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Genetic engineering. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Medical biochemistry. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Cell biology. |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Life Sciences. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Cell Biology. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Biotechnology. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Molecular Medicine. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Genetic Engineering. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Biochemical Engineering. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Medical Biochemistry. |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Taira, Kazunari. |
| Relator term |
editor. |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Kataoka, Kazunori. |
| Relator term |
editor. |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Niidome, Takuro. |
| Relator term |
editor. |
| 710 2# - ADDED ENTRY--CORPORATE NAME |
|---|
| Corporate name or jurisdiction name as entry element |
SpringerLink (Online service) |
| 773 0# - HOST ITEM ENTRY |
|---|
| Title |
Springer eBooks |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY |
|---|
| Relationship information |
Printed edition: |
| International Standard Book Number |
9784431251224 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS |
|---|
| Uniform Resource Identifier |
http://dx.doi.org/10.1007/4-431-27879-6 |
| 912 ## - |
|---|
| -- |
ZDB-2-SBL |
