| 000 -LEADER |
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| fixed length control field |
04673nam a22004335i 4500 |
| 001 - CONTROL NUMBER |
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| control field |
978-3-7643-7417-4 |
| 003 - CONTROL NUMBER IDENTIFIER |
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| control field |
DE-He213 |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
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| control field |
20161121230709.0 |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION |
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| fixed length control field |
cr nn 008mamaa |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
100301s2006 sz | s |||| 0|eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
|---|
| International Standard Book Number |
9783764374174 |
| -- |
978-3-7643-7417-4 |
| 024 7# - OTHER STANDARD IDENTIFIER |
|---|
| Standard number or code |
10.1007/3-7643-7417-9 |
| Source of number or code |
doi |
| 050 #4 - LIBRARY OF CONGRESS CALL NUMBER |
|---|
| Classification number |
R-RZ |
| 072 #7 - SUBJECT CATEGORY CODE |
|---|
| Subject category code |
MBGR |
| Source |
bicssc |
| 072 #7 - SUBJECT CATEGORY CODE |
|---|
| Subject category code |
MED000000 |
| Source |
bisacsh |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER |
|---|
| Classification number |
610 |
| Edition number |
23 |
| 245 10 - TITLE STATEMENT |
|---|
| Title |
NPY Family of Peptides in Neurobiology, Cardiovascular and Metabolic Disorders: from Genes to Therapeutics |
| Medium |
[electronic resource] / |
| Statement of responsibility, etc. |
edited by Zofia Zukowska, Giora Z. Feuerstein. |
| 264 #1 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE |
|---|
| Place of production, publication, distribution, manufacture |
Basel : |
| Name of producer, publisher, distributor, manufacturer |
Birkh�user Basel, |
| Date of production, publication, distribution, manufacture, or copyright notice |
2006. |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Extent |
X, 280 p. |
| Other physical details |
online resource. |
| 336 ## - CONTENT TYPE |
|---|
| Content type term |
text |
| Content type code |
txt |
| Source |
rdacontent |
| 337 ## - MEDIA TYPE |
|---|
| Media type term |
computer |
| Media type code |
c |
| Source |
rdamedia |
| 338 ## - CARRIER TYPE |
|---|
| Carrier type term |
online resource |
| Carrier type code |
cr |
| Source |
rdacarrier |
| 347 ## - DIGITAL FILE CHARACTERISTICS |
|---|
| File type |
text file |
| Encoding format |
PDF |
| Source |
rda1 |
| 490 ## - SERIES STATEMENT |
|---|
| Series statement |
Experientia Supplementum ; |
| Volume/sequential designation |
950 |
| 505 ## - FORMATTED CONTENTS NOTE |
|---|
| Formatted contents note |
NPY family of peptides in neurobiology, cardiovascular system and metabolism: genes, diseases and therapeutics -- NPY family of peptides, receptors and processing enzymes -- An overview of neuropeptide Y: pharmacology to molecular biology and receptor localization -- Molecular ligand-receptor interaction of the NPY/PP peptide family -- Physiological and pathophysiological perspectives of the NPY family of peptides -- Modulator role of neuropeptide Y in human vascular sympathetic neuroeffector junctions -- NPY and NPY receptors: presence, distribution and roles in the regulation of the endocardial endothelium and cardiac function -- Neuropeptide Y and sympathetic control of vascular tone in hypertension -- Neuropeptide Y and the cerebral circulation -- Neuropeptide Y and the heart: implication for myocardial infarction and heart failure -- Role of neuropeptide Y in the regulation of kidney function -- NPY and neuron-adipocyte interactions in the regulation of metabolism -- NPY and energy homeostasis: an opportunity for novel anti-obesity therapies -- Subjugation of hypothalamic NPY and cohorts with central leptin gene therapy alleviates dyslipidemia, insulin resistance, and obesity for life-time -- NPY and bone -- NPY in alcoholism and psychiatric disorders -- Plasticity of neuropeptide Y in the dentate gyrus after seizures, and its relevance to seizure-induced neurogenesis -- NPY and extreme stress: lessons learned from posttraumatic stress disorder -- NPY and chronic neurodegenerative disease -- Genetics of the NPY family of peptides and their receptors -- Human NPY gene variants in cardiovascular and metabolic diseases -- Summary -- Future directions and perspectives for therapies based on the NPY family of peptides. |
| 520 ## - SUMMARY, ETC. |
|---|
| Summary, etc. |
The NPY-family of peptides encompasses several groups of neurotransmitters and hormones, which exert diverse biological and pathological actions that bear on all major vital systems. This book is a unique compilation of the most recent breakthroughs in NPY/PYY neurobiology, cardiovascular and metabolic disorders. The identification of multiple receptors for the members of the NPY and PYY family of peptides provides new opportunities for discovery of specific NPY antagonists and agonists that have vast clinical potential. The recognition of the role of NPY in stimulation of food intake has already resulted in discovery of potent and selective NPY receptor Y-5 antagonists, which are in clinical development for obesity. NPY Y1 receptor antagonists are targeted for cardiovascular indications. Research into the multiple functions of NPY and its receptors in neurological and affective disorders is also actively pursued. The chapters in this book are written by internationally renowned experts with the objective to synthesize leading concepts and data in support for translational medicine. The ideal complement to this volume is the book NPY Family of Peptides in Immune Disorders, Inflammation, Angiogenesis, and Cancer, recently published by the same editors in the Birkh�user book series Progress in Inflammation Research. Both volumes together give a comprehensive overview of the NPY family of peptides. . 0 |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Medicine.14 |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Biomedicine.24 |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Biomedicine general.1 |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Zukowska, Zofia. |
| Relator term |
editor.1 |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Feuerstein, Giora Z. |
| Relator term |
editor.2 |
| 710 ## - ADDED ENTRY--CORPORATE NAME |
|---|
| Corporate name or jurisdiction name as entry element |
SpringerLink (Online service)0 |
| 773 ## - HOST ITEM ENTRY |
|---|
| Title |
Springer eBooks08 |
| 776 ## - ADDITIONAL PHYSICAL FORM ENTRY |
|---|
| Relationship information |
Printed edition: |
| International Standard Book Number |
9783764371555 0 |
| 830 ## - SERIES ADDED ENTRY--UNIFORM TITLE |
|---|
| Uniform title |
Experientia Supplementum ; |
| Volume/sequential designation |
9540 |
| 856 ## - ELECTRONIC LOCATION AND ACCESS |
|---|
| Uniform Resource Identifier |
http://dx.doi.org/10.1007/3-7643-7417-9 |
| 912 ## - |
|---|
| -- |
ZDB-2-SBL |
