| 000 -LEADER |
|---|
| fixed length control field |
03273nam a22004575i 4500 |
| 001 - CONTROL NUMBER |
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| control field |
978-3-540-32952-7 |
| 003 - CONTROL NUMBER IDENTIFIER |
|---|
| control field |
DE-He213 |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
|---|
| control field |
20161121230708.0 |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION |
|---|
| fixed length control field |
cr nn 008mamaa |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
|---|
| fixed length control field |
100301s2006 gw | s |||| 0|eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
|---|
| International Standard Book Number |
9783540329527 |
| -- |
978-3-540-32952-7 |
| 024 7# - OTHER STANDARD IDENTIFIER |
|---|
| Standard number or code |
10.1007/3-540-32952-8 |
| Source of number or code |
doi |
| 050 #4 - LIBRARY OF CONGRESS CALL NUMBER |
|---|
| Classification number |
QR46 |
| 072 #7 - SUBJECT CATEGORY CODE |
|---|
| Subject category code |
MMFM |
| Source |
bicssc |
| 072 #7 - SUBJECT CATEGORY CODE |
|---|
| Subject category code |
MED052000 |
| Source |
bisacsh |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER |
|---|
| Classification number |
616.9041 |
| Edition number |
23 |
| 245 14 - TITLE STATEMENT |
|---|
| Title |
The Myc/Max/Mad Transcription Factor Network |
| Medium |
[electronic resource] / |
| Statement of responsibility, etc. |
edited by R. N. Eisenman. |
| 264 #1 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE |
|---|
| Place of production, publication, distribution, manufacture |
Berlin, Heidelberg : |
| Name of producer, publisher, distributor, manufacturer |
Springer Berlin Heidelberg, |
| Date of production, publication, distribution, manufacture, or copyright notice |
2006. |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Extent |
VII, 282 p. |
| Other physical details |
online resource. |
| 336 ## - CONTENT TYPE |
|---|
| Content type term |
text |
| Content type code |
txt |
| Source |
rdacontent |
| 337 ## - MEDIA TYPE |
|---|
| Media type term |
computer |
| Media type code |
c |
| Source |
rdamedia |
| 338 ## - CARRIER TYPE |
|---|
| Carrier type term |
online resource |
| Carrier type code |
cr |
| Source |
rdacarrier |
| 347 ## - DIGITAL FILE CHARACTERISTICS |
|---|
| File type |
text file |
| Encoding format |
PDF |
| Source |
rda |
| 490 1# - SERIES STATEMENT |
|---|
| Series statement |
Current Topics in Microbiology and Immunology, |
| International Standard Serial Number |
0070-217X ; |
| Volume/sequential designation |
302 |
| 505 0# - FORMATTED CONTENTS NOTE |
|---|
| Formatted contents note |
Making Myc -- Transcriptional Activation by the Myc Oncoprotein -- Mechanisms of Transcriptional Repression by Myc -- The Mad Side of the Max Network: Antagonizing the Function of Myc and More -- Structural Aspects of Interactions Within the Myc/Max/Mad Network -- Myc Target Transcriptomes -- c-Myc, Genome Instability, and Tumorigenesis: The Devil Is in the Details -- Lessons Learned from Myc/Max/Mad Knockout Mice -- Myc/Max/Mad in Invertebrates: The Evolution of the Max Network -- The Mlx Network: Evidence for a Parallel Max-Like Transcriptional Network That Regulates Energy Metabolism. |
| 520 ## - SUMMARY, ETC. |
|---|
| Summary, etc. |
Intense study of the enigmatic myc proto-oncogene over the last 20 years has broadened our view of its functions and led to insights into transcriptional regulation as well as cancer etiology, cell proliferation, apoptosis, and organismal development. How can one gene be involved in so many aspects of cellular behavior? Of particular interest is the fact that the Myc protein functions as part of a network (comprising Myc, Max, and Mad proteins) whose specific interactions direct transcriptional activation or repression of a large number of target genes. The chapters in this volume examine both molecular and biological aspects of the Myc/Max/Mad network. Included are contributions concerning the regulation of its expression, the mechanisms underlying its diverse transcriptional activities, the structural bases for its critical interactions, and the nature of its target genes. Other chapters explore the evolution of the network, its role in development and genomic instability, and the evidence for a parallel transcriptional network. Overall, this volume provides a broad and current overview of research on a crucial group of transcription factors. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Medicine. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Human genetics. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Medical microbiology. |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Biomedicine. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Medical Microbiology. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Human Genetics. |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Eisenman, R. N. |
| Relator term |
editor. |
| 710 2# - ADDED ENTRY--CORPORATE NAME |
|---|
| Corporate name or jurisdiction name as entry element |
SpringerLink (Online service) |
| 773 0# - HOST ITEM ENTRY |
|---|
| Title |
Springer eBooks |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY |
|---|
| Relationship information |
Printed edition: |
| International Standard Book Number |
9783540239680 |
| 830 #0 - SERIES ADDED ENTRY--UNIFORM TITLE |
|---|
| Uniform title |
Current Topics in Microbiology and Immunology, |
| International Standard Serial Number |
0070-217X ; |
| Volume/sequential designation |
302 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS |
|---|
| Uniform Resource Identifier |
http://dx.doi.org/10.1007/3-540-32952-8 |
| 912 ## - |
|---|
| -- |
ZDB-2-SBL |
