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Innervation of the Mammalian Esophagus (Record no. 502584)

000 -LEADER
fixed length control field 03783nam a22004215i 4500
001 - CONTROL NUMBER
control field 978-3-540-32948-0
003 - CONTROL NUMBER IDENTIFIER
control field DE-He213
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20161121230708.0
007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION
fixed length control field cr nn 008mamaa
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 100301s2006 gw | s |||| 0|eng d
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 9783540329480
-- 978-3-540-32948-0
024 7# - OTHER STANDARD IDENTIFIER
Standard number or code 10.1007/978-3-540-32948-0
Source of number or code doi
050 #4 - LIBRARY OF CONGRESS CALL NUMBER
Classification number R-RZ
072 #7 - SUBJECT CATEGORY CODE
Subject category code MBGR
Source bicssc
072 #7 - SUBJECT CATEGORY CODE
Subject category code MED000000
Source bisacsh
082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER
Classification number 610
Edition number 23
245 10 - TITLE STATEMENT
Title Innervation of the Mammalian Esophagus
Medium [electronic resource] /
Statement of responsibility, etc. edited by W.L. Neuhuber.
264 #1 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE
Place of production, publication, distribution, manufacture Berlin, Heidelberg :
Name of producer, publisher, distributor, manufacturer Springer Berlin Heidelberg,
Date of production, publication, distribution, manufacture, or copyright notice 2006.
300 ## - PHYSICAL DESCRIPTION
Extent X, 76 p. 14 illus.
Other physical details online resource.
336 ## - CONTENT TYPE
Content type term text
Content type code txt
Source rdacontent
337 ## - MEDIA TYPE
Media type term computer
Media type code c
Source rdamedia
338 ## - CARRIER TYPE
Carrier type term online resource
Carrier type code cr
Source rdacarrier
347 ## - DIGITAL FILE CHARACTERISTICS
File type text file
Encoding format PDF
Source rda
490 1# - SERIES STATEMENT
Series statement Advances in Anatomy, Embryology and Cell Biology,
International Standard Serial Number 0301-5556 ;
Volume/sequential designation 185
505 0# - FORMATTED CONTENTS NOTE
Formatted contents note Introduction -- Muscle layers of the esophagus -- Materials and Methods. Anterograde WGA-HRP tracing from nodose ganglion. Anterograde DiI tracing from thoracic dorsal root ganglia -- Extrinsic innervation. Vagal innervation -- Spinal innervation. Innervation of esophageal sphincters. Swallowing central pattern generator. Cortical representation of the esophagus in human -- Intrinsic innervation. General organization. Enteric coinnervation -- Functional considerations. General remarks. Cooperation between extrinsic and intrinsic systems -- Concluding remarks -- Summary -- References -- Subject Index.
520 ## - SUMMARY, ETC.
Summary, etc. Understanding the innervation of the esophagus is a prerequisite for successful treatment of a variety of disorders, e.g., dysphagia, achalasia, gastroesophageal reflux disease (GERD) and non-cardiac chest pain. Although, at first glance, functions of the esophagus are relatively simple, their neuronal control is considerably complex. Vagal motor neurons of the nucleus ambiguus and preganglionic neurons of the dorsal motor nucleus innervate striated and smooth muscle, respectively. Myenteric neurons represent the interface between the dorsal motor nucleus and smooth muscle but are also involved in striated muscle innervation. Intraganglionic laminar endings (IGLEs) represent mechanosensory vagal afferent terminals. They also establish intricate connections with enteric neurons. Afferent information is implemented by the swallowing central pattern generator in the brainstem, which generates and coordinates deglutitive activity in both striated and smooth esophageal muscle and orchestrates esophageal sphincters as well as gastric adaptive relaxation. Disturbed excitation/inhibition balance in the lower esophageal sphincter results in motility disorders, e.g., achalasia and gastroesophageal reflux disease. Loss of mechanosensory afferents disrupts adaptation of deglutitive motor programs to bolus variables, eventually leading to megaesophagus. Both spinal and vagal afferents appear to contribute to painful sensations, e.g., non-cardiac chest pain. Extrinsic and intrinsic neurons may be involved in intramural reflexes using acetylcholine, nitric oxide, substance P, CGRP and glutamate as main transmitters. In addition, other molecules, e.g., ATP, GABA and probably also inflammatory cytokines may modulate these neuronal functions.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Medicine.
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Biomedicine.
650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Biomedicine general.
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Neuhuber, W.L.
Relator term editor.
710 2# - ADDED ENTRY--CORPORATE NAME
Corporate name or jurisdiction name as entry element SpringerLink (Online service)
773 0# - HOST ITEM ENTRY
Title Springer eBooks
776 08 - ADDITIONAL PHYSICAL FORM ENTRY
Relationship information Printed edition:
International Standard Book Number 9783540292050
830 #0 - SERIES ADDED ENTRY--UNIFORM TITLE
Uniform title Advances in Anatomy, Embryology and Cell Biology,
International Standard Serial Number 0301-5556 ;
Volume/sequential designation 185
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier http://dx.doi.org/10.1007/978-3-540-32948-0
912 ## -
-- ZDB-2-SBL
Holdings
Withdrawn status Lost status Damaged status Not for loan Permanent Location Current Location Date acquired Barcode Date last seen Price effective from Koha item type
        PK Kelkar Library, IIT Kanpur PK Kelkar Library, IIT Kanpur 2016-11-21 EBK2871 2016-11-21 2016-11-21 E books

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