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08270nam a22004335i 4500 |
| 001 - CONTROL NUMBER |
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| control field |
978-1-59259-963-9 |
| 003 - CONTROL NUMBER IDENTIFIER |
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| control field |
DE-He213 |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
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| control field |
20161121230637.0 |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION |
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cr nn 008mamaa |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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100301s2006 xxu| s |||| 0|eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
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| International Standard Book Number |
9781592599639 |
| -- |
978-1-59259-963-9 |
| 024 7# - OTHER STANDARD IDENTIFIER |
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| Standard number or code |
10.1007/978-1-59259-963-9 |
| Source of number or code |
doi |
| 050 #4 - LIBRARY OF CONGRESS CALL NUMBER |
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| Classification number |
RC1-1245 |
| 072 #7 - SUBJECT CATEGORY CODE |
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| Subject category code |
MJ |
| Source |
bicssc |
| 072 #7 - SUBJECT CATEGORY CODE |
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| Subject category code |
MED045000 |
| Source |
bisacsh |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER |
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| Classification number |
616 |
| Edition number |
23 |
| 245 10 - TITLE STATEMENT |
|---|
| Title |
Principles of Molecular Medicine |
| Medium |
[electronic resource] / |
| Statement of responsibility, etc. |
edited by Marschall S. Runge, Cam Patterson. |
| 250 ## - EDITION STATEMENT |
|---|
| Edition statement |
Second Edition. |
| 264 #1 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE |
|---|
| Place of production, publication, distribution, manufacture |
Totowa, NJ : |
| Name of producer, publisher, distributor, manufacturer |
Humana Press, |
| Date of production, publication, distribution, manufacture, or copyright notice |
2006. |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Extent |
LIV, 1268 p. |
| Other physical details |
online resource. |
| 336 ## - CONTENT TYPE |
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| Content type term |
text |
| Content type code |
txt |
| Source |
rdacontent |
| 337 ## - MEDIA TYPE |
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| Media type term |
computer |
| Media type code |
c |
| Source |
rdamedia |
| 338 ## - CARRIER TYPE |
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| Carrier type term |
online resource |
| Carrier type code |
cr |
| Source |
rdacarrier |
| 347 ## - DIGITAL FILE CHARACTERISTICS |
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| File type |
text file |
| Encoding format |
PDF |
| Source |
rda |
| 505 0# - FORMATTED CONTENTS NOTE |
|---|
| Formatted contents note |
Genetics -- Mendelian Inheritance -- Nontraditional Inheritance -- Identifying Causal Genetic Factors -- Cancer Genetics and Molecular Oncology -- Pharmacogenetics -- Hemophilia as a Model Disease for Gene Therapy of Genetic Disorders -- Genetic Counseling -- Animal Models in Biomedical Research -- Ethical, Legal, and Social Implications -- Cardiology -- Congenital Heart Disease -- Inherited Cardiomyopathies -- Heart Failure -- Aortic Diseases -- Atherosclerotic Coronary Disease -- Lipid Metabolism and Coronary Artery Disease -- Hypertension -- Cardiac Hypertrophy -- Arrhythmias -- Genomics -- Cardiovascular Gene Therapy -- Pulmonary Diseases -- Idiopathic Interstitial Pneumonias -- Asthma -- Pulmonary Emphysema -- Pulmonary Hypertension -- Acute Lung Injury -- Primary Ciliary Dyskinesia -- Cystic Fibrosis -- Gene Therapy for Lung Diseases -- Sarcoidosis -- Disorders of Pulmonary Surfactant Homeostasis -- Endocrinology -- Mechanisms of Hormone Action -- Diabetes Mellitus -- Pituitary Function and Neoplasia -- Growth Hormone Deficiency Disorders -- Thyroid Disorders -- Disorders of the Parathyroid Gland -- Congenital Adrenal Hyperplasia -- Adrenal Diseases -- Multiple Endocrine Neoplasia Type 1 -- Multiple Endocrine Neoplasia Type 2 -- Disorders of Sex Determination and Differentiation -- Sex Chromosome Disorders -- Disorders of Pubertal Development -- Defects of Androgen Action -- Molecular Endocrinology of the Testis -- Ovarian Diseases -- Metabolic Disorders -- Gastrointestinal Regulation of Food Intake -- Cellular Regulation of Lipolysis -- Fat-Induced Insulin Resistance and Atherosclerosis -- Metabolic and Molecular Aspects of Sarcopenia -- Adipose Tissue Development and Metabolism -- Gastroenterology -- Hepatitis C -- Molecular Diagnostics in Hepatitis B -- Hereditary Hemochromatosis -- Pancreatic Exocrine Dysfunction -- Small and Large Bowel Dysfunction -- The Molecular Mechanisms of Helicobacter pylori-Associated Gastroduodenal Disease -- Nephrology -- Nitric Oxide Synthase and Cyclooxygenase in the Kidneys -- Hypertension and Sodium Channel Turnover -- Nephrogenic Diabetes Insipidus st[Water and Urea Transport -- Glomerulonephritis and Smad Signaling -- Interstitial Nephritis -- The Pathophysiology of Acute Renal Failure -- Loss of Lean Body Mass in Uremia -- Mechanisms of Renal Allograft Rejection -- Musculoskeletal -- Muscle Development and Differentiation -- Skeletal Muscle Structure and Function -- Stem Cells and Muscle Regeneration -- Skeletal Muscle Hypertrophy and Response to Training -- Muscular Dystrophies -- Rhabdomyosarcomas -- Oncology -- Apoptosis -- Colorectal Cancer -- Breast Cancer -- Lung Cancer -- Discoveries and Frontiers in Prostate Cancer Translational Sciences -- Cutaneous Melanoma -- Applications of Gene Expression Profiling to the Study of Malignant Gliomas -- Acute Myeloid Leukemias -- Acute Lymphoblastic Leukemia -- Chronic Myelogenous Leukemia -- Non-Hodgkin’s Lymphoma and Chronic Lymphocytic Leukemia -- Multiple Myeloma -- HIV-1, AIDS, and Related Malignancies -- Hematology -- Disorders of the Red Cell Membrane -- Paroxysmal Nocturnal Hemoglobinuria -- Iron Metabolism -- Correction of Genetic Blood Defects by Gene Transfer -- Bone Marrow Failure Syndromes -- Coagulation Disorders -- Advances in Transfusion Safety -- Immunology And Infectious Diseases -- Immunomodulation -- HIV Molecular Biology, Treatment Resistance -- Cellular and Molecular Aspects of Pneumonia -- Molecular Pathogenesis of Fungal Infections -- Dermatology -- Psoriasis -- Atopic Dermatitis -- Pemphigus Foliaceus, Pemphigus Vulgaris, Paraneoplastic Pemphigus, Bullous Pemphigoid, Herpes Gestationis, and Cicatricial Pemphigoid -- Systemic Lupus Erythematosus -- Systemic Sclerosis -- Diseases With Signaling and Transcriptional Abnormalities -- Genetic Skin Diseases With Neoplasia -- Melanoma and Nevi -- Disorders of Hypopigmentation -- Epidermolysis Bullosa -- Connective Tissue Disorders -- Genetic Epidermal Diseases -- Genetic Hair and Nail Defects -- Metabolic Genetic DisordersWith Prominent Skin Findings -- Heritable Conditions Affecting Tissues of the Oral Cavity -- Neurology -- The Genetic Basis of Human Cerebral Cortical Malformations -- Muscular Dystrophies -- Channelopathies of the Nervous System -- Charcot-Marie-Tooth Disease and Related Peripheral Neuropathies -- Amyotrophic Lateral Sclerosis and Related Motor Neuron Disorders -- Trinucleotide Repeat Disorders -- Parkinson’s Disease -- Genetics and Neurobiology of Alzheimer’s Disease and Frontotemporal Dementias -- Prion Diseases -- Narcolepsy and Other Neurological Sleep Disorders -- Neurofibromatosis 1 and 2 -- Axonal Regeneration and Recovery From Chronic Central Nervous System Injury -- Psychiatry -- Molecular Mechanisms Regulating Behavior -- The Complex Genetics of Psychiatric Disorders -- Treating Depression -- Anxiety Disorders -- Trauma Spectrum Disorders -- Schizophrenia -- Disorders of Substance Abuse and Dependence -- Autism and Related Disorders. |
| 520 ## - SUMMARY, ETC. |
|---|
| Summary, etc. |
Marschall S. Runge, MD, PhD, Cam Patterson, MD, and a panel of 251 authoritative contributors-many of them world-renowned clinicians and researchers-have now updated and expanded the much-acclaimed first edition of Principles of Molecular Medicine to provide an integrated survey of the basic principles of internal medicine in the light of recent dramatic discoveries in molecular medicine and new technologies for the diagnosis and treatment of human disease. This second edition contains new sections on genetics, oncology, metabolic diseases, and infectious diseases, in addition to fully revised sections on neurology, cardiology, hematology, nephrology, endocrinology, dermatology, immunology, gastroenterology, pulmonary disease, musculoskeletal medicine, and psychiatry. Here, the reader will discover the latest findings about direct links between genetic mutations and diseases, genomic approaches to a variety of diseases, and stem cell populations that regenerate muscle, heart, and neural cell populations. Other advances elucidated include the roles of bone morphogenetic proteins in pulmonary hypertension, mutations involved in an array of cardiomyopathies, and new understanding of the biology of previously untreatable neurodegenerative diseases, such as Huntington's disease. For this edition, the authors have also focused on producing a tightly written text with more useful figures and tables and reduced references, so that the text is more immediately useful but not overwhelming as a reference book. A CD-ROM edition of the book (ISBN: 1-58829-929-5) is available separately. Comprehensive and state-of-the-art, Principles of Molecular Medicine, Second Edition, offers practicing physicians, researchers, and residents an extraordinary summary of the rapidly emerging molecular mechanisms underlying disease and valuable insights into the nature and direction of future developments. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Medicine. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Internal medicine. |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Medicine & Public Health. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Internal Medicine. |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Runge, Marschall S. |
| Relator term |
editor. |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Patterson, Cam. |
| Relator term |
editor. |
| 710 2# - ADDED ENTRY--CORPORATE NAME |
|---|
| Corporate name or jurisdiction name as entry element |
SpringerLink (Online service) |
| 773 0# - HOST ITEM ENTRY |
|---|
| Title |
Springer eBooks |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY |
|---|
| Relationship information |
Printed edition: |
| International Standard Book Number |
9781588292025 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS |
|---|
| Uniform Resource Identifier |
http://dx.doi.org/10.1007/978-1-59259-963-9 |
| 912 ## - |
|---|
| -- |
ZDB-2-SME |
