| 000 -LEADER |
|---|
| fixed length control field |
04309nam a22004455i 4500 |
| 001 - CONTROL NUMBER |
|---|
| control field |
978-0-387-27826-1 |
| 003 - CONTROL NUMBER IDENTIFIER |
|---|
| control field |
DE-He213 |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
|---|
| control field |
20161121230634.0 |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION |
|---|
| fixed length control field |
cr nn 008mamaa |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
|---|
| fixed length control field |
100301s2006 xxu| s |||| 0|eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
|---|
| International Standard Book Number |
9780387278261 |
| -- |
978-0-387-27826-1 |
| 024 7# - OTHER STANDARD IDENTIFIER |
|---|
| Standard number or code |
10.1007/0-387-27826-5 |
| Source of number or code |
doi |
| 050 #4 - LIBRARY OF CONGRESS CALL NUMBER |
|---|
| Classification number |
RC681-688.2 |
| 072 #7 - SUBJECT CATEGORY CODE |
|---|
| Subject category code |
MJD |
| Source |
bicssc |
| 072 #7 - SUBJECT CATEGORY CODE |
|---|
| Subject category code |
MED010000 |
| Source |
bisacsh |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER |
|---|
| Classification number |
616.12 |
| Edition number |
23 |
| 245 14 - TITLE STATEMENT |
|---|
| Title |
The Local Cardiac Renin Angiotensin-Aldosterone System |
| Medium |
[electronic resource] / |
| Statement of responsibility, etc. |
edited by Edward D. Frohlich, Richard N. Re. |
| 264 #1 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE |
|---|
| Place of production, publication, distribution, manufacture |
Boston, MA : |
| Name of producer, publisher, distributor, manufacturer |
Springer US, |
| Date of production, publication, distribution, manufacture, or copyright notice |
2006. |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Extent |
XVI, 224 p. |
| Other physical details |
online resource. |
| 336 ## - CONTENT TYPE |
|---|
| Content type term |
text |
| Content type code |
txt |
| Source |
rdacontent |
| 337 ## - MEDIA TYPE |
|---|
| Media type term |
computer |
| Media type code |
c |
| Source |
rdamedia |
| 338 ## - CARRIER TYPE |
|---|
| Carrier type term |
online resource |
| Carrier type code |
cr |
| Source |
rdacarrier |
| 347 ## - DIGITAL FILE CHARACTERISTICS |
|---|
| File type |
text file |
| Encoding format |
PDF |
| Source |
rda |
| 490 1# - SERIES STATEMENT |
|---|
| Series statement |
Basic Science for the Cardiologist, |
| International Standard Serial Number |
1566-0753 ; |
| Volume/sequential designation |
20 |
| 505 0# - FORMATTED CONTENTS NOTE |
|---|
| Formatted contents note |
Hypertensive Heart Disease: Time for New Paradigms -- Cardiac (Pro)Renin Receptors: Functional Properties and Potential Significance -- On the Relationship Between the Renin Receptor and the Vacuolar Proton-Atpase Membrane Sector-Associated Protein (M8-9) -- Role of the AT2 Receptor in Cardiovascular Function: A Brief Synopsis -- Regulation of Renin in JGA and Tubules in Hypertension -- Salt Loading: A Paradigm for a Local Cardiac Renin-Angiotensin-Aldosterone System -- Lessons from Experimental Generation of Intracellular Angiotensinogen and AII -- On the Cardiac Renin Angiotensin System: the Heart as a Source of Angiotensin II -- The Hematopoietic System: A New Niche for the Renin-Angiotensin System -- Mechanical Signaling and the Cardiac Renin-angiotensin -- Angiotensin Converting Enzyme 2: A Critical Regulator of the Renin-Angiotensin System -- Dyslipidemia and Angiotensin II and Atherogenesis -- Ace Inhibitors Directly Activate Bradykinin B1 Receptors to Release NO -- Remodeling in Hypertensive Heart Disease: Role of the Renin-Angiotensin-Aldosterone System -- Cardiac Aldosterone Production: A Vascular Problem? -- Cellular Oxidative Stress, Aging, and the Local RAS. |
| 520 ## - SUMMARY, ETC. |
|---|
| Summary, etc. |
How exciting it is to see a field so well established as the ren- angiotensin system continue to grow and mature. Originally, following the original identification of renin by Tigerstedt and Bergman over 100 years ago, workers in this area spent years attempting to establish its role in experimental and renal hypertension. The early work by Goldblatt, in 1934, demonstrated that the placement of a clip around a renal artery was clearly related to the subsequent development of hypertension. However, it wasn't until the simultaneous finding by two different geographically separated teams, Page, et al, in the United States and Braun-Menendez, et al, in Argentina that the peptide angiotensin was identified. Thus, the rate-limiting enzyme renin was released from the kidney and catalyzed a biochemical cascade which was eventually shown to produce the elevated arterial pressure. Subsequently, many workers contributed to the elucidation of the concept and sequence of angiotensin I1 generation. Thus, the enzyme renin acted upon its protein substrate, produced in the liver, to liberate the decapeptide angiotensin I which, upon circulating through the pulmonary circulation, finally produced the potent octapeptide angiotensin. Several important subsequent findings demonstrated that angiotensin I1 promoted the release of the adrenal corticosteroid from that gland, thereby resulting in a larger system, the renin-angiotensin-aldosterone system. Further, this system demonstrated a classical biofeedback and the circulating octapeptide was shown to have additional biological activities in organs other than heart, vessels, kidney, adrenals, and even brain. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Medicine. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Cardiology. |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Medicine & Public Health. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Cardiology. |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Frohlich, Edward D. |
| Relator term |
editor. |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Re, Richard N. |
| Relator term |
editor. |
| 710 2# - ADDED ENTRY--CORPORATE NAME |
|---|
| Corporate name or jurisdiction name as entry element |
SpringerLink (Online service) |
| 773 0# - HOST ITEM ENTRY |
|---|
| Title |
Springer eBooks |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY |
|---|
| Relationship information |
Printed edition: |
| International Standard Book Number |
9780387278254 |
| 830 #0 - SERIES ADDED ENTRY--UNIFORM TITLE |
|---|
| Uniform title |
Basic Science for the Cardiologist, |
| International Standard Serial Number |
1566-0753 ; |
| Volume/sequential designation |
20 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS |
|---|
| Uniform Resource Identifier |
http://dx.doi.org/10.1007/0-387-27826-5 |
| 912 ## - |
|---|
| -- |
ZDB-2-SME |
