000 -LEADER |
fixed length control field |
03326nam a22004935i 4500 |
001 - CONTROL NUMBER |
control field |
978-0-387-26283-3 |
003 - CONTROL NUMBER IDENTIFIER |
control field |
DE-He213 |
005 - DATE AND TIME OF LATEST TRANSACTION |
control field |
20161121230634.0 |
007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION |
fixed length control field |
cr nn 008mamaa |
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
fixed length control field |
100301s2006 xxu| s |||| 0|eng d |
020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
International Standard Book Number |
9780387262833 |
-- |
978-0-387-26283-3 |
024 7# - OTHER STANDARD IDENTIFIER |
Standard number or code |
10.1007/b137303 |
Source of number or code |
doi |
050 #4 - LIBRARY OF CONGRESS CALL NUMBER |
Classification number |
RC254-282 |
072 #7 - SUBJECT CATEGORY CODE |
Subject category code |
MJCL |
Source |
bicssc |
072 #7 - SUBJECT CATEGORY CODE |
Subject category code |
MED062000 |
Source |
bisacsh |
082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER |
Classification number |
616.994 |
Edition number |
23 |
245 14 - TITLE STATEMENT |
Title |
The Link Between Inflammation and Cancer |
Medium |
[electronic resource] : |
Remainder of title |
Wounds that do not heal / |
Statement of responsibility, etc. |
edited by Angus G. Dalgleish, Burkhard Haefner. |
264 #1 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE |
Place of production, publication, distribution, manufacture |
Boston, MA : |
Name of producer, publisher, distributor, manufacturer |
Springer US, |
Date of production, publication, distribution, manufacture, or copyright notice |
2006. |
300 ## - PHYSICAL DESCRIPTION |
Extent |
XII, 254 p. |
Other physical details |
online resource. |
336 ## - CONTENT TYPE |
Content type term |
text |
Content type code |
txt |
Source |
rdacontent |
337 ## - MEDIA TYPE |
Media type term |
computer |
Media type code |
c |
Source |
rdamedia |
338 ## - CARRIER TYPE |
Carrier type term |
online resource |
Carrier type code |
cr |
Source |
rdacarrier |
347 ## - DIGITAL FILE CHARACTERISTICS |
File type |
text file |
Encoding format |
PDF |
Source |
rda |
490 1# - SERIES STATEMENT |
Series statement |
Cancer Treatment and Research, |
International Standard Serial Number |
0927-3042 ; |
Volume/sequential designation |
130 |
505 0# - FORMATTED CONTENTS NOTE |
Formatted contents note |
Inflammation and Cancer -- Chronic Inflammation and Pathogenesis of GI and Pancreatic Cancers -- Cytokines, NF-?B, Microenvironment, Intestinal Inflammation and Cancer -- Regulation if NF-?B Transcriptional Activity -- The Role of Immune Cells in the Tumor Microenvironment -- Tumor-Microenvironment Interactions -- CD95L/FasL and TRAIL in Tumour Surveillance and Cancer Therapy -- Infection & Neoplastic Growth 101 -- Cytokines as Mediators and Targets for Cancer Cachexia -- Targeting NF-?B in Anticancer Adjunctive Chemotherapy. |
520 ## - SUMMARY, ETC. |
Summary, etc. |
The transcription factor NF-kB has long been known to play a central role in the immune system by regulating the expression of key genes. Moreover, activation of this transcription factor helps a wide variety of cell types survive damage induced by pro-apoptotic stimuli. Owing to its critical role in the regulation of pro-inflammatory genes, NF-kB has long been regarded as a promising target for the discovery of anti-inflammatory drugs. More recently, NF-kB has emerged as a major culprit in a variety of human cancers mainly due to its ability to protect transformed cells from apoptosis. This finding should not have come as a surprise since there exists a link between inflammation and many types of cancer which was already suggested by Galen and later demonstrated by Virchow. This link, of crucial importance for the design of novel strategies for cancer treatment, is the topic of this book. Series Editor Cover Comments: "Inflammation is a known risk factor for a number of cancers. In this text, experts discuss the pathophysiology and molecular alterations that link these two processes. Potential therapeutics and preventive strategies are discussed." Steven T. Rosen, M.D. Series Editor. |
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Medicine. |
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Cancer research. |
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Laboratory medicine. |
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Oncology. |
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Medicine & Public Health. |
650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Oncology. |
650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Cancer Research. |
650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Laboratory Medicine. |
700 1# - ADDED ENTRY--PERSONAL NAME |
Personal name |
Dalgleish, Angus G. |
Relator term |
editor. |
700 1# - ADDED ENTRY--PERSONAL NAME |
Personal name |
Haefner, Burkhard. |
Relator term |
editor. |
710 2# - ADDED ENTRY--CORPORATE NAME |
Corporate name or jurisdiction name as entry element |
SpringerLink (Online service) |
773 0# - HOST ITEM ENTRY |
Title |
Springer eBooks |
776 08 - ADDITIONAL PHYSICAL FORM ENTRY |
Relationship information |
Printed edition: |
International Standard Book Number |
9780387262826 |
830 #0 - SERIES ADDED ENTRY--UNIFORM TITLE |
Uniform title |
Cancer Treatment and Research, |
International Standard Serial Number |
0927-3042 ; |
Volume/sequential designation |
130 |
856 40 - ELECTRONIC LOCATION AND ACCESS |
Uniform Resource Identifier |
http://dx.doi.org/10.1007/b137303 |
912 ## - |
-- |
ZDB-2-SME |