| 000 -LEADER |
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| fixed length control field |
03293nam a22004335i 4500 |
| 001 - CONTROL NUMBER |
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| control field |
978-0-387-28295-4 |
| 003 - CONTROL NUMBER IDENTIFIER |
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| control field |
DE-He213 |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
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| control field |
20161121230618.0 |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION |
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| fixed length control field |
cr nn 008mamaa |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
100301s2006 xxu| s |||| 0|eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
|---|
| International Standard Book Number |
9780387282954 |
| -- |
978-0-387-28295-4 |
| 024 7# - OTHER STANDARD IDENTIFIER |
|---|
| Standard number or code |
10.1007/0-387-28295-5 |
| Source of number or code |
doi |
| 050 #4 - LIBRARY OF CONGRESS CALL NUMBER |
|---|
| Classification number |
Q1-390 |
| 072 #7 - SUBJECT CATEGORY CODE |
|---|
| Subject category code |
YQS |
| Source |
bicssc |
| 072 #7 - SUBJECT CATEGORY CODE |
|---|
| Subject category code |
SCI000000 |
| Source |
bisacsh |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER |
|---|
| Classification number |
500 |
| Edition number |
23 |
| 100 1# - MAIN ENTRY--PERSONAL NAME |
|---|
| Personal name |
Dronamraju, Krishna R. |
| Relator term |
author. |
| 245 10 - TITLE STATEMENT |
|---|
| Title |
Malaria: Genetic and Evolutionary Aspects |
| Medium |
[electronic resource] / |
| Statement of responsibility, etc. |
by Krishna R. Dronamraju, Paolo Arese. |
| 264 #1 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE |
|---|
| Place of production, publication, distribution, manufacture |
Boston, MA : |
| Name of producer, publisher, distributor, manufacturer |
Springer US, |
| Date of production, publication, distribution, manufacture, or copyright notice |
2006. |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Extent |
XI, 190 p. 26 illus. |
| Other physical details |
online resource. |
| 336 ## - CONTENT TYPE |
|---|
| Content type term |
text |
| Content type code |
txt |
| Source |
rdacontent |
| 337 ## - MEDIA TYPE |
|---|
| Media type term |
computer |
| Media type code |
c |
| Source |
rdamedia |
| 338 ## - CARRIER TYPE |
|---|
| Carrier type term |
online resource |
| Carrier type code |
cr |
| Source |
rdacarrier |
| 347 ## - DIGITAL FILE CHARACTERISTICS |
|---|
| File type |
text file |
| Encoding format |
PDF |
| Source |
rda |
| 490 1# - SERIES STATEMENT |
|---|
| Series statement |
Emerging Infectious Diseases of the 21st Century |
| 505 0# - FORMATTED CONTENTS NOTE |
|---|
| Formatted contents note |
J.B.S. Haldane (1892–1964) -- Removal of Early Parasite Forms from Circulation as a Mechanism of Resistance Against Malaria in Widespread Red Blood Cell Mutations -- Clinical, Epidemiological, and Genetic Investigations on Thalassemia and Malaria in Italy -- Resistance to Antimalarial Drugs: Parasite and Host Genetic Factors -- Evolutionary Origins of Human Malaria Parasites -- Vector Genetics in Malaria Control -- The Rate of Mutations of Human Genes -- Disease and Evolution. |
| 520 ## - SUMMARY, ETC. |
|---|
| Summary, etc. |
This book was originally conceived at a conference at the University of Turin in Italy. The conference was organized to examine the so-called “Malaria Hypothesis”, that is to say, the higher fitness of t- lassemia heterozygotes in a malarial environment, and to pay tribute to the proponent of that hypothesis, J.B.S. Haldane. Contributors to this book examine certain genetic and evolutionary aspects of malaria which is a major killer of human populations, especially in Africa and Asia. There were attempts to discredit Haldane’s contribution from two directions: (a) it has been suggested that the “Malaria Hypothesis” was known long before Haldane and that there was nothing original about his idea (Lederberg 1999), and that (b) the hypothesis of heterozygote su- riority was first suggested by the Italian biologist Giuseppe Montalenti who communicated his idea to Haldane (Allison 2004). Surely, both c- not be right. In fact, the evidence presented in this book clearly indicates that both are wrong. Haldane’s malaria hypothesis has stimulated a great deal of research on the genetic, evolutionary and epidemiological aspects of malaria d- ing the last 50 years. It has opened up a whole new chapter in the study of infectious diseases. It deserves serious consideration. For helpful discussions we thank Lucio Luzzatto, Alberto Piazza, Guido Modiano and David Roberts. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Science. |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Science. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Science, general. |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Arese, Paolo. |
| Relator term |
author. |
| 710 2# - ADDED ENTRY--CORPORATE NAME |
|---|
| Corporate name or jurisdiction name as entry element |
SpringerLink (Online service) |
| 773 0# - HOST ITEM ENTRY |
|---|
| Title |
Springer eBooks |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY |
|---|
| Relationship information |
Printed edition: |
| International Standard Book Number |
9780387282947 |
| 830 #0 - SERIES ADDED ENTRY--UNIFORM TITLE |
|---|
| Uniform title |
Emerging Infectious Diseases of the 21st Century |
| 856 40 - ELECTRONIC LOCATION AND ACCESS |
|---|
| Uniform Resource Identifier |
http://dx.doi.org/10.1007/0-387-28295-5 |
| 912 ## - |
|---|
| -- |
ZDB-2-SHU |
