| 000 -LEADER |
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| fixed length control field |
04449nam a22004695i 4500 |
| 001 - CONTROL NUMBER |
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| control field |
978-1-59259-883-0 |
| 003 - CONTROL NUMBER IDENTIFIER |
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| control field |
DE-He213 |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
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| control field |
20161121230555.0 |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION |
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| fixed length control field |
cr nn 008mamaa |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
100301s2005 xxu| s |||| 0|eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
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| International Standard Book Number |
9781592598830 |
| -- |
978-1-59259-883-0 |
| 024 7# - OTHER STANDARD IDENTIFIER |
|---|
| Standard number or code |
10.1385/1592598838 |
| Source of number or code |
doi |
| 050 #4 - LIBRARY OF CONGRESS CALL NUMBER |
|---|
| Classification number |
RC681-688.2 |
| 072 #7 - SUBJECT CATEGORY CODE |
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| Subject category code |
MJD |
| Source |
bicssc |
| 072 #7 - SUBJECT CATEGORY CODE |
|---|
| Subject category code |
MED010000 |
| Source |
bisacsh |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER |
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| Classification number |
616.12 |
| Edition number |
23 |
| 245 10 - TITLE STATEMENT |
|---|
| Title |
Cardiovascular Genomics |
| Medium |
[electronic resource] / |
| Statement of responsibility, etc. |
edited by Mohan K. Rai, Julian F. R. Paton, Sergey Kasparov, Michael J. Katovich. |
| 264 #1 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE |
|---|
| Place of production, publication, distribution, manufacture |
Totowa, NJ : |
| Name of producer, publisher, distributor, manufacturer |
Humana Press, |
| Date of production, publication, distribution, manufacture, or copyright notice |
2005. |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Extent |
XIV, 362 p. |
| Other physical details |
online resource. |
| 336 ## - CONTENT TYPE |
|---|
| Content type term |
text |
| Content type code |
txt |
| Source |
rdacontent |
| 337 ## - MEDIA TYPE |
|---|
| Media type term |
computer |
| Media type code |
c |
| Source |
rdamedia |
| 338 ## - CARRIER TYPE |
|---|
| Carrier type term |
online resource |
| Carrier type code |
cr |
| Source |
rdacarrier |
| 347 ## - DIGITAL FILE CHARACTERISTICS |
|---|
| File type |
text file |
| Encoding format |
PDF |
| Source |
rda |
| 490 1# - SERIES STATEMENT |
|---|
| Series statement |
Contemporary Cardiology |
| 505 0# - FORMATTED CONTENTS NOTE |
|---|
| Formatted contents note |
Genes and Polymorphisms in Cardiovascular Disease -- Angiotensin II Receptor Polymorphisms and Hypertension -- Angiotensinogen Gene Polymorphisms and Hypertension -- Substitution Mapping -- Local Production of Angiotensinogen -- Cardiovascular Pharmacogenomics -- Genetic Polymorphisms and Response to HMG-CoA Reductase Inhibitors -- Monogenic Causes of Heart Failure -- Gene Transfer for Combating Cardiovascular Disease -- Gene Therapy vs Pharmacotherapy -- Molecular Therapeutic Approaches for Myocardial Protection -- Gene Transfer and the Cardiovascular System -- Kallikrein Gene Transfer in Hypertension, Cardiovascular and Renal Disease, and Stroke -- Current and Future Novel Targets of Gene Therapy for Hypertension -- Application of Viral Gene Transfer in Studies of Neurogenic Hypertension -- Vigilant Vectors -- Gene Therapy for Celebral Arterial Diseases -- Regenerative Tissues for the Diseased Cardiovascular System -- Therapeutic Angiogenesis and Vasculogenesis for Tissue Regeneration -- Cell Transplantation -- Embryonic Stem Cells and the Cardiovascular System. |
| 520 ## - SUMMARY, ETC. |
|---|
| Summary, etc. |
After more than 50 years of limited success in controlling blood pressure with traditional antihypertensive drugs, the time is ripe to explore alternate strategies for managing cardiovascular diseases. In Cardiovascular Genomics, recognized scientists and clinicians from around the world discuss the most recent molecular approaches to understanding the cardiovascular system in both health and disease. The authors focus on all components of the system, including blood vessels, heart, kidneys, and the brain, and cover disease states ranging from vascular and cardiac dysfunction to stroke and hypertension. The methods described for identifying the genes that cause susceptibility to cardiovascular diseases emphasize the possibility of discovering new drug targets. They involve genetic linkage analysis and substitution mapping using congenic strains, microarray techniques, and strategies for discovery in animal models of hypertension. The new transgenic mouse models that either over- or underexpress angiotensinogen are used to illuminate the function of the tissue renin-angiotensin systems, enhancing the understanding of the role of polymorphisms, a crucial factor for effective design of new drugs. The chapters on gene transfer and gene therapy cover a wide variety of topics ranging from novel clinical applications for treating stroke, coronary, and peripheral vascular diseases, to producing new cardiovascular cells and tissues, to using viral vectors as tools. A value-added compact disk containing a companion ebook version of Cardiovascular Genomics is included for downloading and use in the reader's PC or PDA. Authoritative and ground-breaking, Cardiovascular Genomics offers an unprecedented examination of both cutting-edge scientific approaches through the new science of cardiovascular genomics, and the efficacious results it is now possible to obtain. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Medicine. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Cardiology. |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Medicine & Public Health. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Cardiology. |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Rai, Mohan K. |
| Relator term |
editor. |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Paton, Julian F. R. |
| Relator term |
editor. |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Kasparov, Sergey. |
| Relator term |
editor. |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Katovich, Michael J. |
| Relator term |
editor. |
| 710 2# - ADDED ENTRY--CORPORATE NAME |
|---|
| Corporate name or jurisdiction name as entry element |
SpringerLink (Online service) |
| 773 0# - HOST ITEM ENTRY |
|---|
| Title |
Springer eBooks |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY |
|---|
| Relationship information |
Printed edition: |
| International Standard Book Number |
9781588294005 |
| 830 #0 - SERIES ADDED ENTRY--UNIFORM TITLE |
|---|
| Uniform title |
Contemporary Cardiology |
| 856 40 - ELECTRONIC LOCATION AND ACCESS |
|---|
| Uniform Resource Identifier |
http://dx.doi.org/10.1385/1592598838 |
| 912 ## - |
|---|
| -- |
ZDB-2-SME |
